Hypertension management in high risk type II diabetes with CKD: Insights from recent trials with a focus on albuminuria. A case based discussion  Matthew Weir  Journal of Indian College of Cardiology  Volume 5, Pages S104-S109 (March 2015) DOI: 10.1016/j.jicc.2015.03.021 Copyright © 2015 Indian College of Cardiology Terms and Conditions

Fig. 1 Annual transition rates through stages of albuminuria in patients with type 2 diabetes. Source: Adler A, et al. Kidney Int. 2003;63:225–32 Journal of Indian College of Cardiology 2015 5, S104-S109DOI: (10.1016/j.jicc.2015.03.021) Copyright © 2015 Indian College of Cardiology Terms and Conditions

Fig. 2 RENAAL: proteinuria reduction at month 6 determines the cardiovascular outcome. Source: De Zeeuw et al. Circulation. 2004;110:921–927 Journal of Indian College of Cardiology 2015 5, S104-S109DOI: (10.1016/j.jicc.2015.03.021) Copyright © 2015 Indian College of Cardiology Terms and Conditions

Fig. 3 Yearly average clinic systolic blood pressure (mmHg). Journal of Indian College of Cardiology 2015 5, S104-S109DOI: (10.1016/j.jicc.2015.03.021) Copyright © 2015 Indian College of Cardiology Terms and Conditions

Fig. 4 Occurrence of microalbuminuria during the 48-month follow-up period in the two study groups. Source: Haller H, et al. N Engl J Med 2011;364:907–17 Journal of Indian College of Cardiology 2015 5, S104-S109DOI: (10.1016/j.jicc.2015.03.021) Copyright © 2015 Indian College of Cardiology Terms and Conditions

Fig. 5 IRMA 2 primary endpoint development of overt proteinuria. Journal of Indian College of Cardiology 2015 5, S104-S109DOI: (10.1016/j.jicc.2015.03.021) Copyright © 2015 Indian College of Cardiology Terms and Conditions