Biochemical cartilage alteration and unexpected signal recovery in T2

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Presentation transcript:

Biochemical cartilage alteration and unexpected signal recovery in T2 Biochemical cartilage alteration and unexpected signal recovery in T2* mapping observed in ankle joints with mobile MRI during a transcontinental multistage footrace over 4486 km U.H.W. Schütz, J. Ellermann, D. Schoss, H. Wiedelbach, M. Beer, C. Billich Osteoarthritis and Cartilage Volume 22, Issue 11, Pages 1840-1850 (November 2014) DOI: 10.1016/j.joca.2014.08.001 Copyright © 2014 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 MR-image post-processing for quantification of thickness and T2* relaxation time of TTJ cartilage: A: sagittal FLASH T2*w GRE: (1) tibia, (2) talus, (3) calcaneus, (4) navicular, (5) cuboid, (6) ankle joint, (7) subtalar joint, (8) talonavicular joint, (9) calcaneocuboidal joint. B: fused colored T2* GRE map (syngo™ MapIt fusion technique): colored visualization of T2* in tibial plafond and talar dome cartilage of the ankle joint. C: cartilage thickness [mm] measurement of ankle joint (anterior, central and posterior in each slice). Osteoarthritis and Cartilage 2014 22, 1840-1850DOI: (10.1016/j.joca.2014.08.001) Copyright © 2014 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 T2*-mapping of TTJ (relaxation time): Absolute values of measures of variation (nF = 13). Osteoarthritis and Cartilage 2014 22, 1840-1850DOI: (10.1016/j.joca.2014.08.001) Copyright © 2014 Osteoarthritis Research Society International Terms and Conditions

Fig. 3 T2*-mapping of TTJ: Relative changes of T2* relaxation times of single and aggregated segments compared to start (finisher group; nF = 13). Osteoarthritis and Cartilage 2014 22, 1840-1850DOI: (10.1016/j.joca.2014.08.001) Copyright © 2014 Osteoarthritis Research Society International Terms and Conditions

Fig. 4 Osteochondral lesions (yellow arrow) in the ankle joint. Sagittal TIRM slices through TTJ: A: of a 59-years-old male finisher (1: baseline, 2: stage 32/2176 km run, 3: stage 53/3669 km run, 4: 8 months after TEFR) B: of a 49-years-old male non-finisher (1: baseline, 2: stage 19/1260 km run, 3:stage 31/2131 km run, 4: stage 53/3669 km run) C: of a 46-years-old male finisher (1: baseline, 2: stage 52/3609 km run) and a 68-years-old female non-finisher (3: baseline, 4: stage 15/1003 km run) D: of a 34-years-old male finisher (1: baseline, 2: stage 18/1192 km run, 3:stage 29/1985 km run, 4: stage 54/3763 km run). Osteoarthritis and Cartilage 2014 22, 1840-1850DOI: (10.1016/j.joca.2014.08.001) Copyright © 2014 Osteoarthritis Research Society International Terms and Conditions