Multimodality treatment of unresectable stage III non–small cell lung cancer: Interim analysis of a phase II trial with preoperative gemcitabine and concurrent.

Slides:

Advertisements

Similar presentations

Improved survival with pulmonary metastasectomy: An analysis of 1720 patients with pulmonary metastatic melanoma Rebecca P. Petersen, MD, MSc, Steven.

Advertisements

The evolution of treatment outcomes for resected stage IIIA non–small cell lung cancer over 16 years at a single institution Linda W. Martin, MD, Arlene.

Stephen R. Broderick, MD, MPHS

Is lung cancer resection indicated in patients with idiopathic pulmonary fibrosis? Atsushi Watanabe, MD, PhD, Tetsuya Higami, MD, PhD, Syunsuke Ohori,

Endovascular stent grafting versus open surgical repair of descending thoracic aortic aneurysms in low-risk patients: A multicenter comparative trial

The eighth edition TNM stage classification for lung cancer: What does it mean on main street? Frank C. Detterbeck, MD The Journal of Thoracic and Cardiovascular.

Michael Y. Chang, MD, MPH, Steven J. Mentzer, MD, Yolonda L

One in every 14 patients with early-stage lung cancer is not being treated! Benny Weksler, MD, MBA The Journal of Thoracic and Cardiovascular Surgery

It is not just about surgery versus stereotactic ablative radiotherapy, it is about curing as many patients with lung cancer as possible Alessandro Brunelli,

Surgical Treatment in Patient with Non–Small-Cell Lung Cancer with Fissure Involvement: Anatomical versus Nonanatomical Resection Giovanni Leuzzi, MD,

Effect of tumor size on prognosis in patients with non–small cell lung cancer: The role of segmentectomy as a type of lesser resection Morihito Okada,

Long-Term Results after Treatment for Recurrent Thymoma: A Multicenter Analysis Alberto Sandri, Giacomo Cusumano, Filippo Lococo, MD, Marco Alifano, Pierluigi.

Preresection serum C-reactive protein measurement and survival among patients with resectable non–small cell lung cancer Marco Alifano, MD, PhD, Pierre.

Malignant Solitary Fibrous Tumors of the Pleura: Retrospective Review of a Multicenter Series Filippo Lococo, MD, Alfredo Cesario, MD, Giuseppe Cardillo,

Prognostic significance of histologic differentiation, carcinoembryonic antigen value, and lymphovascular invasion in stage I non–small cell lung cancer

Paul J. Scheel, BS, Traves D. Crabtree, MD, Jennifer M

Impact of tumor size on outcomes after anatomic lung resection for stage 1A non–small cell lung cancer based on the current staging system Shamus R.

Multimodality Treatment of Stage III Non-small Cell Lung Cancer: Analysis of a Phase II Trial Using Preoperative Cisplatin and Gemcitabine with Concurrent.

Radical sublobar resection for small-sized non–small cell lung cancer: A multicenter study Morihito Okada, MD, PhD, Teruaki Koike, MD, PhD, Masahiko.

The prognostic impact of microRNA sequence polymorphisms on the recurrence of patients with completely resected non–small cell lung cancer Kyong-Ah Yoon,

Outcomes of unexpected pathologic N1 and N2 disease after video-assisted thoracic surgery lobectomy for clinical stage I non–small cell lung cancer Hong.

Surgery for oligometastatic non–small cell lung cancer: Long-term results from a single center experience Maria Teresa Congedo, MD, Alfredo Cesario,

Centers for Disease Control “increased-risk” organ donor: Not so risky? Francis D. Pagani, MD, PhD The Journal of Thoracic and Cardiovascular Surgery

John M. Varlotto, MD, Abram Recht, MD, John C. Flickinger, MD, Laura N

Victor van Berkel, MD, PhD

Patterns of survival and recurrence after surgical treatment of early stage non–small cell lung carcinoma in the ACOSOG Z0030 (ALLIANCE) trial Stacey.

Metformin exposure is associated with improved progression-free survival in diabetic patients after resection for early-stage non–small cell lung cancer

The lord of the rings Antonio Miceli, MD, PhD

Esophagectomy versus endoscopic resection for patients with early-stage adenocarcinoma: Mercedes versus Tesla Toni Lerut, MD The Journal of Thoracic.

Yang Zhang, MD, Haiquan Chen, MD, PhD

Aditya K. Kaza, MD The Journal of Thoracic and Cardiovascular Surgery

Impact of positive pleural lavage cytology on survival in patients having lung resection for non–small-cell lung cancer: An international individual patient.

Small-bore wire-guided chest drains: Safety, tolerability, and effectiveness in pneumothorax, malignant effusions, and pleural empyema Stefano Cafarotti,

A first start for lung transplantation?

Pulmonary inverted schneiderian papilloma

Stephen R. Broderick, MD, MPHS

Are discordant positron emission tomography and pathological assessments of the mediastinum in non–small cell lung cancer significant? Daniel J. Tandberg,

Resection of primary lung cancer with incidental pleural seeding: Seeds of change or reap what you sow? Jules Lin, MD The Journal of Thoracic and Cardiovascular.

Living without lungs? Bilateral pneumonectomy and dual circulatory support: A step forward in the search for a total artificial lung Christian A. Bermudez,

Niv Ad, MD, Lawrence M. Wei, MD

Internal validation of risk models in lung resection surgery: Bootstrap versus training- and-test sampling Alessandro Brunelli, MD, Gaetano Rocco, MD

Adjuvant Surgery after Carboplatin and VP16 in Resectable Small Cell Lung Cancer Giulia Veronesi, MD, Paolo Scanagatta, MD, Francesco Leo, MD, Tommaso.

Video-assisted resection for lung cancer results in fewer complications Lunxu Liu, PhD, MD, FRCS The Journal of Thoracic and Cardiovascular Surgery

Phase II trial of postoperative adjuvant cisplatin and etoposide in patients with completely resected stage I-IIIa small cell lung cancer: The Japan Clinical.

Passing the torch The Journal of Thoracic and Cardiovascular Surgery

Patients with unbalanced atrioventricular canal defects can undergo the Fontan operation with good outcomes Sitaram M. Emani, MD The Journal of Thoracic.

Development of a patient-centered aggregate score to predict survival after lung resection for non–small cell lung cancer Alessandro Brunelli, MD, Michele.

Improved survival with pulmonary metastasectomy: An analysis of 1720 patients with pulmonary metastatic melanoma Rebecca P. Petersen, MD, MSc, Steven.

The Journal of Thoracic and Cardiovascular Surgery

Discussion The Journal of Thoracic and Cardiovascular Surgery

The future of cardiac surgery training: A survival guide

Linda W. Martin, MD, MPH, FCCP, FACS, Gail E

Robert J. Cerfolio, MD, FACS, FCCP, Ayesha S. Bryant, MSPH, MD

The Robin Hood principle in the treatment of congenital heart disease: Taking technologic developments intended for adults and using it in kids Paul.

Large clinical databases for the study of lung cancer: Making up for the failure of randomized trials Chi-Fu Jeffrey Yang, MD, Matthew G. Hartwig, MD,

Aritoshi Hattori, MD, Kenji Suzuki, MD

Ryan R. Davies, MD The Journal of Thoracic and Cardiovascular Surgery

Lung cancer randomized controlled trials should compare stereotactic body radiation therapy with observation, NOT surgery Raja M. Flores, MD The Journal.

Salvage surgery for advanced non–small cell lung cancer after response to gefitinib Tomoyuki Hishida, MD, Kanji Nagai, MD, Tetsuya Mitsudomi, MD, Kohei.

Preoperative PFTs: The answer is blowing in the wind

European Society of Thoracic Surgeons preoperative mediastinal staging guidelines: From face validity to external validity Alessandro Brunelli, MD The.

Who should decide margin length in pulmonary excision of lung cancer?

Is there a benefit to continuing with resection of all sites of disease when clinically occult pleural metastases from non–small cell carcinoma are found?

Samuel Kim, MD The Journal of Thoracic and Cardiovascular Surgery

Is pulmonary function damaged by neoadjuvant lung cancer therapy

Journal changes and initiatives

Induction Therapy Followed by Surgery for T3-T4/N0 Non-Small Cell Lung Cancer: Long-Term Results Filippo Lococo, MD, Alfredo Cesario, MD, Stefano Margaritora,

Local Control and Toxicity of Adaptive Radiotherapy Using Weekly CT Imaging: Results from the LARTIA Trial in Stage III NSCLC Sara Ramella, MD, Michele.

Reappraise the advanced technique for tumor localization and sentinel lymph node assessment in clinical early-stage non–small cell lung cancer Chengwu.

Kristin A. Higgins, MD, Junzo P. Chino, MD, Neal Ready, MD, Mark W

Presentation transcript:

Multimodality treatment of unresectable stage III non–small cell lung cancer: Interim analysis of a phase II trial with preoperative gemcitabine and concurrent radiotherapy Domenico Galetta, MD, Alfredo Cesario, MD, Stefano Margaritora, MD, Venanzio Porziella, MD, Alessio Piraino, MD, Rolando M. D’Angelillo, MD, Maria A. Gambacorta, MD, Sara Ramella, MD, Lucio Trodella, MD, Salvatore Valente, Giuseppe M. Corbo, Giuseppe Macis, Antonino Mulè, Vittorio Cardaci, MD, Silvia Sterzi, MD, Pierluigi Granone, MD, Patrizia Russo, PhD The Journal of Thoracic and Cardiovascular Surgery Volume 131, Issue 2, Pages 314-321.e3 (February 2006) DOI: 10.1016/j.jtcvs.2005.07.044 Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions

Figure E1 Treatment plan. GEM, Gemcitabine. The Journal of Thoracic and Cardiovascular Surgery 2006 131, 314-321.e3DOI: (10.1016/j.jtcvs.2005.07.044) Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions

Figure E2 Survival curve of all eligible patients. Numbers at bottom indicate patients at risk. The Journal of Thoracic and Cardiovascular Surgery 2006 131, 314-321.e3DOI: (10.1016/j.jtcvs.2005.07.044) Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions

Figure E3 Survival curves for patients with resected (R, solid line) versus nonresected (NR, dotted line) disease. Numbers at bottom indicate patients at risk. The Journal of Thoracic and Cardiovascular Surgery 2006 131, 314-321.e3DOI: (10.1016/j.jtcvs.2005.07.044) Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions

Figure E4 Disease-free survival among patients undergoing resection. Numbers at bottom indicate patients at risk. The Journal of Thoracic and Cardiovascular Surgery 2006 131, 314-321.e3DOI: (10.1016/j.jtcvs.2005.07.044) Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions