One More Piece in the Fibrillin Puzzle

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Presentation transcript:

One More Piece in the Fibrillin Puzzle Dirk Hubmacher, Dieter P. Reinhardt Structure Volume 17, Issue 5, Pages 635-636 (May 2009) DOI: 10.1016/j.str.2009.04.002 Copyright © 2009 Elsevier Ltd Terms and Conditions

Figure 1 Domain Organization of the Human Fibrillin/LTBP Superfamily Members The domains discussed in this preview are indicated in color. Jensen et al. (2009) solved the structure of the hyb2 domain (H2, blue) in the context of its flanking cbEGF9 and cbEGF10 domains as indicated. The hyb1 domain (H1, blue) of all fibrillins contain an additional unpaired ninth cysteine residue, while the hyb domains in LTBPs do not contain such an extra cysteine. For simplicity, only the longest splice variant of each LTBP is displayed. Structure 2009 17, 635-636DOI: (10.1016/j.str.2009.04.002) Copyright © 2009 Elsevier Ltd Terms and Conditions