Kounis syndrome caused by anaphylaxis without skin manifestations after cefazolin administration Hidenori Adachi, MD, Madoka Ihara, MD, PhD, Yuhei Nojima,

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Presentation transcript:

Kounis syndrome caused by anaphylaxis without skin manifestations after cefazolin administration Hidenori Adachi, MD, Madoka Ihara, MD, PhD, Yuhei Nojima, MD, Tetsuya Kurimoto, MD, PhD, Sinsuke Nanto, MD, PhD The Journal of Allergy and Clinical Immunology: In Practice Volume 7, Issue 1, Pages 317-319 (January 2019) DOI: 10.1016/j.jaip.2018.05.030 Copyright © 2019 The Authors Terms and Conditions

Figure 1 The 12-lead electrocardiogram. A, Preoperative electrocardiogram. B, Electrocardiogram during shock showing ST elevation in leads II, III, and aVF. The Journal of Allergy and Clinical Immunology: In Practice 2019 7, 317-319DOI: (10.1016/j.jaip.2018.05.030) Copyright © 2019 The Authors Terms and Conditions

Figure 2 Results of intradermal testing. Intradermal testing showed a strong positive reaction with wheal of 15 × 17 mm and erythema of 28 × 31 mm (white arrow heads) for cefazolin, but negative results for physiological saline, xylocaine, and penicillin. The Journal of Allergy and Clinical Immunology: In Practice 2019 7, 317-319DOI: (10.1016/j.jaip.2018.05.030) Copyright © 2019 The Authors Terms and Conditions