A Microfluidic Device for Conducting Gas-Liquid-Solid Hydrogenation Reactions by Juta Kobayashi, Yuichiro Mori, Kuniaki Okamoto, Ryo Akiyama, Masaharu Ueno, Takehiko Kitamori, and Shū Kobayashi Science Volume 304(5675):1305-1308 May 28, 2004 Published by AAAS

Fig. 1. Ideal device for multiphase reactions. Juta Kobayashi et al. Science 2004;304:1305-1308 Published by AAAS

Fig. 2. Experimental hydrogenation system using a microreactor and immobilization of the Pd catalyst. Experimental hydrogenation system using a microreactor and immobilization of the Pd catalyst. Juta Kobayashi et al. Science 2004;304:1305-1308 Published by AAAS

Fig. 3. The appearance of the reaction system in the microchannel. The appearance of the reaction system in the microchannel. (A) View of the microchannel without catalyst (left) and with the Pd catalyst (right). (B) Triphase reaction system. Juta Kobayashi et al. Science 2004;304:1305-1308 Published by AAAS

Table 1. Hydrogenation using the Pd-immobilized microchannel. Hydrogenation using the Pd-immobilized microchannel. Unless otherwise noted, the reaction conditions were 1 ml/min H2 in THF at room temperature for 2 min, and yields were quantitative (side products are noted) as determined by 1H NMR. Juta Kobayashi et al. Science 2004;304:1305-1308 Published by AAAS