Decrease in oxidative stress and histological changes induced by physical exercise calibrated in rats with osteoarthritis induced by monosodium iodoacetate  D.J. Cifuentes, L.G. Rocha, L.A. Silva, A.C. Brito, C.R. Rueff-Barroso, L.C. Porto, R.A. Pinho  Osteoarthritis and Cartilage  Volume 18, Issue 8, Pages 1088-1095 (August 2010) DOI: 10.1016/j.joca.2010.04.004 Copyright © 2010 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 Illustration showing the three areas of reference used for the histomorphological analysis. Anterior area (1) intermediate area (2) the posterior area (3) The patella is indicated by the arrow. Osteoarthritis and Cartilage 2010 18, 1088-1095DOI: (10.1016/j.joca.2010.04.004) Copyright © 2010 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 Photomicrographs of histomorphological changes of joint cartilage stained by H&E. Normal appearance of joint cartilage (A). Invasion of fibroblastoid infiltrate in the cartilage (B) and the cartilage and subchondral bone (C). Chondrocytes forming strings with elongated collagen fibers in parallel bands giving it the appearance of fibrocartilage (D). Scale A–C=100mm, D=50mm. Osteoarthritis and Cartilage 2010 18, 1088-1095DOI: (10.1016/j.joca.2010.04.004) Copyright © 2010 Osteoarthritis Research Society International Terms and Conditions