Increased incidence of mosaicism detected by FISH in murine blastocyst cultured in vitro  Tanya V. Sabhnani, Aisha Elaimi, Hanan Sultan, Adel Alduraihem,

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Increased incidence of mosaicism detected by FISH in murine blastocyst cultured in vitro  Tanya V. Sabhnani, Aisha Elaimi, Hanan Sultan, Adel Alduraihem, Paul Serhal, Joyce C. Harper  Reproductive BioMedicine Online  Volume 22, Issue 6, Pages 621-631 (June 2011) DOI: 10.1016/j.rbmo.2011.01.011 Copyright © 2011 Reproductive Healthcare Ltd. Terms and Conditions

Figure 1 (A) Murine kidney nuclei, 100×. The expected/normal signals are two green signals representing the presence of two copies of chromosome 2 and two red signals representing the presence of two copies of chromosome 11. (B) Mouse embryonic nuclei, 100×. Blue colour indicates DAPI-stained nucleus. The expected/normal signals are two green signals representing the presence of two copies of chromosome 2 and two red signals representing the presence of two copies of chromosome 11. Other combinations would be considered as abnormal: (a, b) normal/diploid murine embryonic nuclei for chromosomes 2 and 11 obtained after fluorescent in-situ hybridization; (c) trisomy 11; and (d) monosomy 11 obtained after fluorescent in-situ hybridization. Reproductive BioMedicine Online 2011 22, 621-631DOI: (10.1016/j.rbmo.2011.01.011) Copyright © 2011 Reproductive Healthcare Ltd. Terms and Conditions