Dennis R. Holmes, MD, William Wester, BA, Robert W

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Presentation transcript:

Prostaglandin E2 synthesis and cyclooxygenase expression in abdominal aortic aneurysms  Dennis R. Holmes, MD, William Wester, BA, Robert W. Thompson, MD, Jeffrey M. Reilly, MD  Journal of Vascular Surgery  Volume 25, Issue 5, Pages 810-815 (May 1997) DOI: 10.1016/S0741-5214(97)70210-6 Copyright © 1997 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 1 Raw data for ELISA for PGE2. There were ten specimens in each category. Of note is that PGE2 levels in culture media of AAA specimens are in all instances an order of magnitude greater than in normal group. Journal of Vascular Surgery 1997 25, 810-815DOI: (10.1016/S0741-5214(97)70210-6) Copyright © 1997 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 2 Immunohistochemical analysis for PGE2 in AAA tissue. A, Specific staining within macrophage. B, Staining within macrophages and less-intense staining over smooth muscle cells. Journal of Vascular Surgery 1997 25, 810-815DOI: (10.1016/S0741-5214(97)70210-6) Copyright © 1997 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 2 Immunohistochemical analysis for PGE2 in AAA tissue. A, Specific staining within macrophage. B, Staining within macrophages and less-intense staining over smooth muscle cells. Journal of Vascular Surgery 1997 25, 810-815DOI: (10.1016/S0741-5214(97)70210-6) Copyright © 1997 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 3 In situ hybridization for cox2 in AAA tissue. A and B, High-power views of AAA tissue demonstrate the specific staining within macrophage-like cells within inflammatory infiltrate. Journal of Vascular Surgery 1997 25, 810-815DOI: (10.1016/S0741-5214(97)70210-6) Copyright © 1997 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 3 In situ hybridization for cox2 in AAA tissue. A and B, High-power views of AAA tissue demonstrate the specific staining within macrophage-like cells within inflammatory infiltrate. Journal of Vascular Surgery 1997 25, 810-815DOI: (10.1016/S0741-5214(97)70210-6) Copyright © 1997 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions