Joseph A. Murray, Stela McLachlan, Paul C. Adams, John H

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Presentation transcript:

Association Between Celiac Disease and Iron Deficiency in Caucasians, but Not Non- Caucasians Joseph A. Murray, Stela McLachlan, Paul C. Adams, John H. Eckfeldt, Chad P. Garner, Chris D. Vulpe, Victor R. Gordeuk, Tricia Brantner, Catherine Leiendecker–Foster, Anthony A. Killeen, Ronald T. Acton, Lisa F. Barcellos, Debbie A. Nickerson, Kenneth B. Beckman, Gordon D. McLaren, Christine E. McLaren Clinical Gastroenterology and Hepatology Volume 11, Issue 7, Pages 808-814 (July 2013) DOI: 10.1016/j.cgh.2013.02.009 Copyright © 2013 AGA Institute Terms and Conditions

Figure 1 Schema for detection of CD status. EMA, endomysial antibody. Clinical Gastroenterology and Hepatology 2013 11, 808-814DOI: (10.1016/j.cgh.2013.02.009) Copyright © 2013 AGA Institute Terms and Conditions

Figure 2 Results of serologic testing for CD in Caucasians and non-Caucasians. Clinical Gastroenterology and Hepatology 2013 11, 808-814DOI: (10.1016/j.cgh.2013.02.009) Copyright © 2013 AGA Institute Terms and Conditions

Figure 3 Percentage of positive celiac serology in iron-deficient cases vs iron-replete controls (Fisher exact test, P = 1.96× 10−6). Clinical Gastroenterology and Hepatology 2013 11, 808-814DOI: (10.1016/j.cgh.2013.02.009) Copyright © 2013 AGA Institute Terms and Conditions

Figure 4 Positive celiac serology in Caucasians and non-Caucasians. All individuals with CD were Caucasian (15 of 1094); CD was absent in non-Caucasians (0 of 609; Fisher exact test, P = .002). Clinical Gastroenterology and Hepatology 2013 11, 808-814DOI: (10.1016/j.cgh.2013.02.009) Copyright © 2013 AGA Institute Terms and Conditions