Osteogenesis Imperfecta By Caden Saizan Duhon Class Hour #3

What is Osteogenesis Imperfecta? Osteogenesis Imperfecta, or brittle bones disease, is a genetic disorder that happens because of a defect in the gene that makes the protein collagen which helps the body build strong bones. Without it, the bones can break easily and deformities can occur. There are, today, 15 kinds of Osteogenesis Imperfecta but there are 4 that most cases of the symptoms fall.

Who does Osteogenesis Imperfecta effect? Osteogenesis Imperfecta, because it is a genetic disorder, the people that are effected by it are born with the disease and have inherited it from a parent that already have the disease. Sometimes, the disorder can happen spontaneously. If someone's grandmother had Osteogenesis Imperfecta then it is possible that she could have passed the gene down to the person’s mother and then down to them.

What are the symptoms of Osteogenesis Imperfecta? The symptoms of Osteogenesis Imperfecta include: bones that break with no known cause or from very minor trauma bone pain bone deformity (such as scoliosis or bowlegs) a shorter stature brittle teeth (called dentinogenetic imperfecta) a blue, purple, or gray tint to the sclera (the whites of the eyes) triangular face shape hearing loss in adulthood loose joints

What part of the body does Osteogenesis Imperfecta effect? Osteogenesis Imperfecta effects the skeletal system. It prevents the bones from growing strong, can cause the bones to break from little to no force, and can cause bone deformities.

What causes Osteogenesis Imperfecta? Osteogenesis Imperfecta is caused by a defect in the gene that makes the protein collagen. The disease makes it so that not enough collagen is produced or the collagen doesn’t work as it should.

What are the cures or treatments for Osteogenesis Imperfecta? Osteogenesis Imperfecta has no cure but does have some treatments. One is physical therapy, which can help young kids learn how to live with the disease. The second is bone strengthening medication to help prevent the bone breaks. Finally, the third is surgery for when the bone actually breaks.

How can we prevent Osteogenesis Imperfecta? There isn’t a way to stop people from getting infected by Osteogenesis Imperfecta, but there is a way, for the most part,to prevent it from ruining peoples lives by treating the person and helping them overcome the disease.

How does Osteogenesis Imperfecta effect people’s lives? Osteogenesis Imperfecta effects a person’s life by making that person have trouble walking and make them be extra careful to not break their bones. Also, the person will go through treatment that will help them live with the disease, like going through physical therapy and taking bone strengthening medicine.

Resources Bober, M. B. (Ed.). (2018, February). Osteogenesis Imperfecta (Brittle Bone Disease). Retrieved November 25, 2018, from https://kidshealth.org/en/parents/osteogenesis- imperfecta.html?ref=search The site has helped with a lot of the research had everything I needed. Guterba, L. Human Body Retrieved November 25, 2018, from https://kidinfo.com/health/human_body.html When I clicked on the link that Osteogenesis Imperfecta would fit under, it brought me to the website that resource one is on. Osteogenesis imperfecta. (2018, November 25). Retrieved November 25, 2018, from https://en.wikipedia.org/wiki/Osteogenesis_imperfecta Used as a secondary source to see if info was the same as source one.