Repetitive oocyte donation does not decrease serum anti-Müllerian hormone levels  Orhan Bukulmez, M.D., Qin Li, M.S., Bruce R. Carr, M.D., Benjamin Leader, M.D., Ph.D., Kathleen M. Doody, M.D., Kevin J. Doody, M.D.  Fertility and Sterility  Volume 94, Issue 3, Pages 905-912 (August 2010) DOI: 10.1016/j.fertnstert.2009.05.017 Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions

Figure 1 Slopes and the test of slope differences among groups 3 (A), 4 (B), 5 (C), and 6 (D) for AMH and cycle trends. Square root of AMH was used for statistics. Solid lines were obtained from repeated-measure multiple regression while controlling for baseline (first cycle) AMH, donor age at the time of each cycle, number of oocytes retrieved per cycle, FSH dose (IU) used per cycle, peak E2, and clinical pregnancy outcome in each cycle. Whereas AMH showed significant increase over repetitive cycles in group 6 (P<.0001), comparisons of the slopes between groups 3, 4, 5, and 6 were not significantly different from each other (P=.90). Therefore, the linear trend of the cycle was not significantly different among the groups. Fertility and Sterility 2010 94, 905-912DOI: (10.1016/j.fertnstert.2009.05.017) Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions

Figure 2 Mean (±SEM) of serum AMH levels over the mean time frame (years) of repetitive cycles according to the maximum number of oocyte donation cycles performed per woman (groups 3, 4, 5, and 6, as given by each line). Although groups showed various basal AMH levels, AMH levels do not decline over the time frame of oocyte donation cycles. The numbers of women in each group are given in parentheses. Fertility and Sterility 2010 94, 905-912DOI: (10.1016/j.fertnstert.2009.05.017) Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions