Indirect effects of childhood pneumococcal conjugate vaccination on invasive pneumococcal disease: a systematic review and meta-analysis Dr Tinevimbo.

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Presentation transcript:

Indirect effects of childhood pneumococcal conjugate vaccination on invasive pneumococcal disease: a systematic review and meta-analysis Dr Tinevimbo Shiri, PhD, Samik Datta, PhD, Jason Madan, PhD, Alexander Tsertsvadze, MD, Pamela Royle, PhD, Prof Matt J Keeling, PhD, Prof Noel D McCarthy, DPhil, Prof Stavros Petrou, PhD The Lancet Global Health Volume 5, Issue 1, Pages e51-e59 (January 2017) DOI: 10.1016/S2214-109X(16)30306-0 Copyright © 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY license Terms and Conditions

Figure 1 Study selection ISPPD 2014=International Symposium on Pneumococci and Pneumococcal Diseases 2014 conference abstracts. PCV=pneumococcal conjugate vaccine. The Lancet Global Health 2017 5, e51-e59DOI: (10.1016/S2214-109X(16)30306-0) Copyright © 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY license Terms and Conditions

Figure 2 Changes in invasive pneumococcal disease due to grouped PCV7 serotypes since introduction of PCV7 into national immunisation programmes PCV7=seven-valent pneumococcal conjugate vaccine. CrI=credible interval. The Lancet Global Health 2017 5, e51-e59DOI: (10.1016/S2214-109X(16)30306-0) Copyright © 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY license Terms and Conditions

Figure 3 Changes in invasive pneumococcal disease due to grouped additional PCV13 serotypes after PCV13 replaced PCV7 PCV7=seven-valent pneumococcal conjugate vaccine. PCV13=13-valent pneumococcal conjugate vaccine. addPCV13= six serotypes in PCV13 not in PCV7. CrI=credible interval. The Lancet Global Health 2017 5, e51-e59DOI: (10.1016/S2214-109X(16)30306-0) Copyright © 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY license Terms and Conditions