RNA-Seeded Functional Amyloids Balance Growth and Survival

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RNA-Seeded Functional Amyloids Balance Growth and Survival Shawn M. Lyons, Paul Anderson Developmental Cell Volume 39, Issue 2, Pages 131-132 (October 2016) DOI: 10.1016/j.devcel.2016.10.005 Copyright © 2016 Terms and Conditions

Figure 1 Stress-Induced Ribonucleoprotein Aggregates A-bodies, described by Audas et al. (2016), are cellular bodies induced by stress and seeded by the expression of non-coding RNAs from the ribosomal RNA loci. Stress granules are sites of stalled translation machinery containing poly(A) mRNA. P-bodies are thought to be sites of mRNA decay because they contain de-adenylated mRNA and are enriched with mRNA decay factors. Nuclear stress granules serve to reprogram gene expression during stress and require the transcription of the satellite III loci. Developmental Cell 2016 39, 131-132DOI: (10.1016/j.devcel.2016.10.005) Copyright © 2016 Terms and Conditions