Change of proinflammatory cytokines follows certain patterns after induction of endometriosis in a mouse model  Qiong-Hua Chen, Ph.D., Wei-Dong Zhou,

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Change of proinflammatory cytokines follows certain patterns after induction of endometriosis in a mouse model  Qiong-Hua Chen, Ph.D., Wei-Dong Zhou, Ph.D., Zhi-Ying Su, M.D., Qian-Sheng Huang, Ph.D., Jin-Na Jiang, M.D., Qing-Xi Chen, Ph.D.  Fertility and Sterility  Volume 93, Issue 5, Pages 1448-1454 (March 2010) DOI: 10.1016/j.fertnstert.2009.02.013 Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions

Figure 1 Morphologic changes of the endometriotic lesions at different days: (A) 2nd day; (B) 4th day; (C) 6th day; (D) 9th day; (E) 15th day; (F) 21st day. Fertility and Sterility 2010 93, 1448-1454DOI: (10.1016/j.fertnstert.2009.02.013) Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions

Figure 2 Change in mRNA level of cytokines over time. All of them reached the first peak on the 1st day, and the second and the third peaks appeared during the time periods from the 3rd day to the 6th day and from the 12th day to the 15th day. IL-1β = interleukin-1β; MCP-1 = monocyte chemoattractant protein 1; TNF-α = tumor necrosis factor α; VEGF = vascular endothelial growth factor. Fertility and Sterility 2010 93, 1448-1454DOI: (10.1016/j.fertnstert.2009.02.013) Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions

Figure 3 Change in the protein level of cytokines over time. All of them arrived at the first peak on the 1st day, and the second and the third peaks appeared during the time period from the 3rd day to the 6th day and from the 12th day to the 15th day. Abbreviations as in Figure 2. Fertility and Sterility 2010 93, 1448-1454DOI: (10.1016/j.fertnstert.2009.02.013) Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions