Bioelectrical impedance in young patients with cystic fibrosis: Validation of a specific equation and clinical relevance A.M. Charatsi, P. Dusser, R.

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Bioelectrical impedance in young patients with cystic fibrosis: Validation of a specific equation and clinical relevance A.M. Charatsi, P. Dusser, R. Freund, G. Maruani, H. Rossin, A. Boulier, M. Le Bourgeois, F. Chedevergne, J. de Blic, A. Letourneur, G. Casimir, J.P. Jais, I. Sermet-Gaudelus Journal of Cystic Fibrosis Volume 15, Issue 6, Pages 825-833 (November 2016) DOI: 10.1016/j.jcf.2016.05.004 Copyright © 2016 European Cystic Fibrosis Society. Terms and Conditions

Fig. 1 On the left: Bland–Altman plot showing the difference of FFM (kg) between the BIA and DXA assessments in CF1 population (N=54). On the right: Bland–Altman plot showing the difference of FM (kg) between the BIA and DXA assessment in CF1 population (N=54). FFMBIA, fat-free mass by bioelectrical impedance analysis; FFMDXA, fat-free mass by dual X-ray absorptiometry; FMBIA, fat mass by bioelectrical impedance analysis; FMDXA, fat mass by dual X-ray absorptiometry; Bias, mean difference; SD, standard deviation. Journal of Cystic Fibrosis 2016 15, 825-833DOI: (10.1016/j.jcf.2016.05.004) Copyright © 2016 European Cystic Fibrosis Society. Terms and Conditions

Fig. 2 Scattergram depicting BMI z-scores for patients with FFM depletion (black triangle; n=9) and without FFM depletion (white circle; n=31). Horizontal lines represent median values of BMI z-scores for the two FFM conditions. *FFM depletion is defined by a FFMBIA z-score≤−2. BMI, body mass index; FFM, fat-free mass. Journal of Cystic Fibrosis 2016 15, 825-833DOI: (10.1016/j.jcf.2016.05.004) Copyright © 2016 European Cystic Fibrosis Society. Terms and Conditions

Fig. 3 Scattergram depicting FMBIA z-scores for patients with FFM depletion (black triangle; n=9) and without FFM depletion (white circle; n=31) and correlation between FFMBIA and FMBIA z-scores. Horizontal lines represent median values of FMBIA z-scores for the two FFM conditions. Pearson's product moment correlation coefficient=0.42 [95% CI, 0.13; 0.65] (p=0.007). *FFM depletion is defined by a FFMBIA z-score≤−2. FM, fat mass; FFM, fat-free mass. Journal of Cystic Fibrosis 2016 15, 825-833DOI: (10.1016/j.jcf.2016.05.004) Copyright © 2016 European Cystic Fibrosis Society. Terms and Conditions