Are unilateral and bilateral knee osteoarthritis patients unique subsets of knee osteoarthritis? A biomechanical perspective  S.P. Messier, D.P. Beavers,

Slides:



Advertisements
Similar presentations
Efficacy of ultrasound therapy for the management of knee osteoarthritis: a systematic review with meta-analysis A. Loyola-Sánchez, J. Richardson, N.J.
Advertisements

Volume 34, Issue 3, Pages (July 2011)
Body mass index affects knee joint mechanics during gait differently with and without moderate knee osteoarthritis  Graeme T. Harding, Cheryl L. Hubley-Kozey,
The association between metacarpal ratio, radiographic hand and knee osteoarthritis and its progression after meniscectomy  P.T. Paradowski, L.S. Lohmander,
Effects of exercise and weight loss on interstitial matrix turnover and tissue inflammation biomarkers in adults with knee osteoarthritis: the intensive.
Contralateral hip and knee gait biomechanics are unchanged by total hip replacement for unilateral hip osteoarthritis  Kharma C. Foucher, Markus A. Wimmer 
Association of urinary metabolites with radiographic progression of knee osteoarthritis in overweight and obese adults: an exploratory study  R.F. Loeser,
The short-term effects of running on the deformation of knee articular cartilage and its relationship to biomechanical loads at the knee  M. Boocock,
Association of baseline knee sagittal dynamic joint stiffness during gait and 2-year patellofemoral cartilage damage worsening in knee osteoarthritis 
Effects of dietary weight loss with and without exercise on interstitial matrix turnover and tissue inflammation biomarkers in adults with knee osteoarthritis:
P.-S. Hsu, H.-H. Lin, C.-R. Li, W.-S. Chung 
A. Bhave, M. Mont, M. Chugthai, R. Starr  Osteoarthritis and Cartilage 
D. J. Bechard, T. B. Birmingham, A. A. Zecevic, I. C. Jones, K. M
Effects of total and regional fat loss on plasma CRP and IL-6 in overweight and obese, older adults with knee osteoarthritis  K.M. Beavers, D.P. Beavers,
Unique spatiotemporal and dynamic gait compensations in the rat monoiodoacetate injection and medial meniscus transection models of knee osteoarthritis 
Knee effusion affects knee mechanics and muscle activity during gait in individuals with knee osteoarthritis  D.J. Rutherford, C.L. Hubley-Kozey, W.D.
A. H. Chang, J. S. Chmiel, K. C. Moisio, O. Almagor, Y. Zhang, S
Avoidance of activity and limitations in activities in patients with osteoarthritis of the hip or knee: a 5 year follow-up study on the mediating role.
Osteoarthritis year 2011 in review: biochemical markers of osteoarthritis: an overview of research and initiatives  Y. Henrotin  Osteoarthritis and Cartilage 
Predictive and concurrent validity of cartilage thickness change as a marker of knee osteoarthritis progression: data from the Osteoarthritis Initiative 
Altered sagittal plane knee kinetics following anterior cruciate ligament injury and reconstruction is associated with knee T1ρ and T2 cartilage relaxation.
Pre-operative interventions (non-surgical and non-pharmacological) for patients with hip or knee osteoarthritis awaiting joint replacement surgery – a.
Transdermal buprenorphine plus oral paracetamol vs an oral codeine-paracetamol combination for osteoarthritis of hip and/or knee: a randomised trial 
High flexion is associated with knee osteoarthritis - of four high flexion postures, flat foot squatting minimizes knee adduction moments  H.C. Chong,
L. McCann, E. Ingham, Z. Jin, J. Fisher  Osteoarthritis and Cartilage 
Time to be positive about negative data?
Osteoarthritis and Cartilage
D. J. Hunter, D. P. Beavers, F. Eckstein, A. Guermazi, R. F. Loeser, B
The effects of body weight unloading on hip and knee biomechanical parameters during overground walking  A.G. Fischer, A. Wolf  Osteoarthritis and Cartilage 
Stem cell therapy for human cartilage defects: a systematic review
S. Sonne-Holm, M.D., Dr. Sci., S. Jacobsen, M.D. 
Knee varus–valgus motion during gait – a measure of joint stability in patients with osteoarthritis?  M. van der Esch, M.A., M. Steultjens, Ph.D., J.
Baseline knee adduction and flexion moments during walking are both associated with 5 year cartilage changes in patients with medial knee osteoarthritis 
Association of urinary metabolites with radiographic progression of knee osteoarthritis in overweight and obese adults: an exploratory study  R.F. Loeser,
Medial arch supports do not significantly alter the knee adduction moment in people with knee osteoarthritis  R.S. Hinman, L. Bardin, M. Simic, K.L. Bennell 
The association between knee joint biomechanics and neuromuscular control and moderate knee osteoarthritis radiographic and pain severity  J.L. Astephen.
Osteoarthritis of the knee after meniscal resection: long term radiographic evaluation of disease progression  P.T. Paradowski, L.S. Lohmander, M. Englund 
Effects of an intensive weight loss program on knee joint loading in obese adults with knee osteoarthritis  J. Aaboe, H. Bliddal, S.P. Messier, T. Alkjær,
Moderators and mediators of effects of unloading shoes on knee pain in people with knee osteoarthritis: an exploratory analysis of the SHARK randomised.
Risk factors for onset of osteoarthritis of the knee in older adults: a systematic review and meta-analysis  M. Blagojevic, C. Jinks, A. Jeffery, K.P.
A graphic user interface for the evaluation of knee osteoarthritis (GEKO): an open- source tool for histological grading  H.E. Kloefkorn, B.Y. Jacobs,
Structural changes in the knee during weight loss maintenance after a significant weight loss in obese patients with osteoarthritis: a report of secondary.
Who should have a joint replacement? A plea for more ‘phronesis’
D.J. Hunter  Osteoarthritis and Cartilage 
Hip strengthening reduces symptoms but not knee load in people with medial knee osteoarthritis and varus malalignment: a randomised controlled trial 
A novel method for assessing signal intensity within infrapatellar fat pad on MR images in patients with knee osteoarthritis  M. Lu, Z. Chen, W. Han,
Associations between patellofemoral joint cartilage T1ρ and T2 and knee flexion moment and impulse during gait in individuals with and without patellofemoral.
Does high weight loss in older adults with knee osteoarthritis affect bone-on-bone joint loads and muscle forces during walking?  S.P. Messier, C. Legault,
D.J. Hunter  Osteoarthritis and Cartilage 
Effects of exercise and weight loss on interstitial matrix turnover and tissue inflammation biomarkers in adults with knee osteoarthritis: the intensive.
S.G. Muthuri, D.F. McWilliams, M. Doherty, W. Zhang 
R. M. Queen, J. E. Carter, S. B. Adams, M. E. Easley, J. K. DeOrio, J
Altered gait mechanics and elevated serum pro-inflammatory cytokines in asymptomatic patients with MRI evidence of knee cartilage loss  S.N. Edd, J. Favre,
Most patients gain weight in the 2 years after total knee arthroplasty: comparison to a healthy control group  J.A. Zeni, L. Snyder-Mackler  Osteoarthritis.
Osteoarthritis and Cartilage
C. Ratzlaff, M. Koehoorn, J. Cibere, J. Kopec 
Osteoarthritis year 2012 in review: biology
Daily cumulative hip moment is associated with radiographic progression of secondary hip osteoarthritis  H. Tateuchi, Y. Koyama, H. Akiyama, K. Goto,
L.A. Deveza, L. Melo, T.P. Yamato, K. Mills, V. Ravi, D.J. Hunter 
L.S. Gates, C.J. Bowen, M.T. Sanchez-Santos, A. Delmestri, N.K. Arden 
Efficacy of rehabilitation programs for improving muscle strength in people with hip or knee osteoarthritis: a systematic review with meta-analysis  A.
Osteoarthritis and Cartilage
E. M. Debbi, B. Bernfeld, E. Gray, M. Salai, Y. Levy, A. Gold, R
Altered biomechanics and cartilage health changes in bilateral knees following unilateral ACL reconstruction: a 2-year follow-up  J.K. Ochoa, K. Amano,
Body mass index affects knee joint mechanics during gait differently with and without moderate knee osteoarthritis  Graeme T. Harding, Cheryl L. Hubley-Kozey,
Osteoarthritis year in review 2016: mechanics
The relationship between foot and ankle symptoms and risk of developing knee osteoarthritis: data from the osteoarthritis initiative  K.L. Paterson, J.
M. Doherty, P. Dieppe  Osteoarthritis and Cartilage 
The effect of eight weeks of exercise on knee adduction moment in early knee osteoarthritis – a pilot study  C.A. Thorstensson, Ph.D., M. Henriksson,
General Information Osteoarthritis and Cartilage
Presentation transcript:

Are unilateral and bilateral knee osteoarthritis patients unique subsets of knee osteoarthritis? A biomechanical perspective  S.P. Messier, D.P. Beavers, C. Herman, D.J. Hunter, P. DeVita  Osteoarthritis and Cartilage  Volume 24, Issue 5, Pages 807-813 (May 2016) DOI: 10.1016/j.joca.2015.12.005 Copyright © 2015 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 Mean (95% CI) sagittal plane (a, b) knee angular position, (c, d) knee moment, and (e, f) knee power vs percent of gait cycle (heel strike = 0%; heel strike of the same foot = 100%) for the unilateral (Uni) and Bilateral (Bi) groups on the most/affected and least/unaffected sides. Mean symmetry indices (SI) for peak knee flexion during stance, peak extension moment, and peak power production and absorption are also noted. Osteoarthritis and Cartilage 2016 24, 807-813DOI: (10.1016/j.joca.2015.12.005) Copyright © 2015 Osteoarthritis Research Society International Terms and Conditions