Characterization and Risk Factor Analysis of Osteoporosis in a Large Cohort of Patients with Chronic Graft-versus-Host Disease  Filip Pirsl, Lauren M. Curtis, Seth M. Steinberg, Sri Harsha Tella, Mašenjka Katić, Marnie Dobbin, Jennifer Hsu, Fran T. Hakim, Jacqueline W. Mays, Annie P. Im, Dražen Pulanić, Sandra A. Mitchell, Judy Baruffaldi, Licia Masuch, David C. Halverson, Ronald E. Gress, Julianna Barsony, Steven Z. Pavletic  Biology of Blood and Marrow Transplantation  Volume 22, Issue 8, Pages 1517-1524 (August 2016) DOI: 10.1016/j.bbmt.2016.04.012 Copyright © 2016 Terms and Conditions

Figure 1 Distribution of bone mineral density (T-scores) at each anatomic site. T-scores at the femoral neck were significantly lower than both lumbar spine and total hip T-scores (P < .0001 for both; indicated by an asterisk), whereas lumbar spine and total hip T-scores were not statistically different from each other (P = .55). FN indicates femoral neck; LS, lumbar spine; TH, total hip. Biology of Blood and Marrow Transplantation 2016 22, 1517-1524DOI: (10.1016/j.bbmt.2016.04.012) Copyright © 2016 Terms and Conditions

Figure 2 Prevalence of osteoporosis and osteopenia. The definition of osteoporosis was based on the World Health Organization criteria. A T-score ≤ −2.5 indicates osteoporosis; −2.5 < T-score < −1.0 indicates osteopenia, and a T-score ≥ −1.0 is normal [31]. N = 258 patients. *For All, patients were defined using the lowest T-score. FN indicates femoral neck; LS, lumbar spine; TH, total hip. Biology of Blood and Marrow Transplantation 2016 22, 1517-1524DOI: (10.1016/j.bbmt.2016.04.012) Copyright © 2016 Terms and Conditions