Sporadic cases of acute autochthonous hepatitis E in Spain

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Sporadic cases of acute autochthonous hepatitis E in Spain Maria Buti, Pilar Clemente-Casares, Rosend Jardi, Meritxell Formiga-Cruz, Melanie Schaper, Auristela Valdes, Francisco Rodriguez- Frias, Rafael Esteban, Rosina Girones  Journal of Hepatology  Volume 41, Issue 1, Pages 126-131 (July 2004) DOI: 10.1016/j.jhep.2004.03.013

Fig. 1 (Left side) Unrooted phylogenetic tree depicting the relationship between the 101 nucleotides analyzed in ORF2 between the HEV strains reported in this study (VH3, VH4 and VH5) and others isolates from genotype 1 (China1,C1; Pakistan, P; India, I; Barcelona, BCN; Burma, B; Chad, Ch; Egypt, Eg; Morocco, Mo), genotype 2 (Mexico, M), genotype 3 (United States, US1, US2 and W1; Greece, G1 and G2; Italy, It; Austria, Au; Nancy, N1; Japan, Jp1 and Jp2; Barcelona, BCN3, BCN4, BCN5, BCN12, BCN16, VH1 and VH2; swine HEV from Barcelona, Por1; swine HEV from the United States, Sw) and genotype 4 (China, C2 and C3). Strains from this study are in black. The internal nodes number represent bootstrap values (1000 replicates) expressed as the percentage of all trees. Only values greater than 60 are represented. (Right side) Unrooted phylogenetic tree depicting the relationship between the 242 nucleotides analyzed in ORF1 between 2 of the HEV strains reported in this study (VH3 and VH5) and others isolates from genotype 1 (China1,C1; Pakistan, P; India, I; Barcelona, BCN; Burma, B; Chad, Ch; Egypt, Eg; Morocco, Mo), genotype 2 (Mexico, M), genotype 3 (United States, US1, US2 and W1; Greece, G1 and G2; Italy, It; Austria, Au; Japan, Jp1 and Jp2; Barcelona, VH1 and VH2; swine HEV from the United States, Sw) and genotype 4 (China, C2 and C3). Strains from this study are in black. The internal nodes number represent bootstrap values (1000 replicates) expressed as the percentage of all trees. Only values greater than 60 are represented. Journal of Hepatology 2004 41, 126-131DOI: (10.1016/j.jhep.2004.03.013)