Bellwork: 9/21 Put your phone up  Week 9/17-9/21 Briefly summarize Madelyn’s story in 1-2 sentences

Today: Finish Anorexia Packet

Materials Anorexia Packet

Homework None 

What happens to our bodies when we intake TOO many macromolecules?

What happens to our bodies when we intake TOO few macromolecules?

Unit II: Biochemistry

Part V: Enzymes

Intro Question Someone says to you “you can eat as much as you want and never gain weight; you must have a high metabolism”. What do you think that statement means biochemically?

Chemical Reaction A process that changes one set of chemicals into another This change comes from breaking and/or forming new chemical bonds

Enzymes Types of proteins Speed up chemical reactions Shapes & function have to match for them to be able to work Speed up chemical reactions A million times faster or more

Enzymes Enzymes make reactions go faster OR slower To adjust metabolism Have names ending in “-ase” Ex. Lactase(enzyme) breaks down Lactose (Sugar)

Think-Pair-Share What happens in the Catalytic Converter in a car? Why is a Catalytic Converter a good name?

How Enzymes Work Each enzyme has a unique shape Works on a specific chemical Substrate = chemical the enzyme works on Each enzyme has an active site VERY SPECIFIC A slot or pocket that fits substrate perfectly

Enzyme

Active Site Shape of Active Site Complementary to shape of Substrate

Lock and Key Model The grooves and prongs of the key Must be complementary to grooves and prongs of the lock Like the Active Site and the Substrate Must be complementary

Environmental Effect Extreme environments can affect enzyme shape & binding of the Substrate 2 key environmental factors High Temperature pH too acidic or too basic These environments cause the enzyme to denature (break down)

Environmental Effect Example: Digestive enzymes break down food Enzymes build starch out of sugar Organisms need 1000s of enzymes Without enzymes, life would not survive