Volume 383, Issue 9935, Pages (June 2014)

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Volume 383, Issue 9935, Pages 2104-2106 (June 2014) Postmastectomy radiation in breast cancer with one to three involved lymph nodes: ending the debate Philip Poortmans The Lancet Volume 383, Issue 9935, Pages 2104-2106 (June 2014) DOI: 10.1016/S0140-6736(14)60192-6 Copyright © 2014 Poortmans. Open Access article distributed under the terms of CC BY-NC-SA Terms and Conditions

Figure Combined hypothetical benefit of local tumour control on survival with increasing effectiveness of systemic therapy (ST) and decreasing risk of distant metastases of the primary tumour Patients in the left part of the slope have high-risk disease without effective systemic therapy and are not expected to benefit from improving locoregional treatments. For patients in the right part of the slope, treatment deintensification (surgery, radiation, or systemic therapy) might be appropriate. The middle group will represent most past and current patients with breast cancer, for whom an optimum multidisciplinary approach results in the greatest benefit. The Lancet 2014 383, 2104-2106DOI: (10.1016/S0140-6736(14)60192-6) Copyright © 2014 Poortmans. Open Access article distributed under the terms of CC BY-NC-SA Terms and Conditions