James J. Yang, PhD, Esteban G

Slides:

Advertisements

Similar presentations

Early exposure to cow's milk protein is protective against IgE-mediated cow's milk protein allergy Yitzhak Katz, MD, Nelly Rajuan, MSc, Michael R. Goldberg,

Advertisements

Control of immunopathology during chikungunya virus infection Caroline Petitdemange, PhD, Nadia Wauquier, PhD, Vincent Vieillard, PhD Journal of Allergy.

Endoplasmic reticulum stress influences bronchial asthma pathogenesis by modulating nuclear factor κB activation So Ri Kim, MD, PhD, Dong Im Kim, MS, Mi.

D-dimer: A biomarker for antihistamine-resistant chronic urticaria

Factors associated with degree of atopy in Latino children in a nationwide pediatric sample: The Genes-environments and Admixture in Latino Asthmatics.

Peter Vadas, MD, PhD, Boris Perelman, PhD, Gary Liss, MD, MS

Genetic variation in B cell–activating factor of the TNF family (BAFF) and asthma exacerbations among African American subjects Rajesh Kumar, MD, MS,

Cosmopolitan and ethnic-specific replication of genetic risk factors for asthma in 2 Latino populations Joshua M. Galanter, MD, Dara Torgerson, PhD,

Risk of an asthma exacerbation after bariatric surgery in adults

Kyoung-Bok Min, MD, PhD, Jin-Young Min, PhD

Fatty acids, inflammation, and asthma

A cluster-randomized trial to provide clinicians inhaled corticosteroid adherence information for their patients with asthma L. Keoki Williams, MD, MPH,

Santa Jeremy Ono, BA, PhD, Mark B. Abelson, MD

Ann-Marie M. Schoos, MD, PhD, Jacob D

Atopic dermatitis: Age and race do matter!

Major rabbit allergen Ory c 3: What could be its possible role as a sensitizing agent in real life? Gennaro Liccardi, MD, Antonello Salzillo, MD, Maria.

Longitudinal variation of serum periostin levels in adults with stable asthma Ruth Semprini, MB BS, Rachel Caswell-Smith, MBChB, James Fingleton, PhD,

Serum vitamin D levels and severe asthma exacerbations in the Childhood Asthma Management Program study John M. Brehm, MD, MPH, Brooke Schuemann, BS,

Applying epidemiologic concepts of primary, secondary, and tertiary prevention to the elimination of racial disparities in asthma Christine L.M. Joseph,

Is 9 more than 2 also in allergic airway inflammation?

Fatty acids, inflammation, and asthma

Albert M. Levin, PhD, Rasika A

Rising prevalence of asthma is sex-specific in a US farming population

Quantifying the proportion of severe asthma exacerbations attributable to inhaled corticosteroid nonadherence L. Keoki Williams, MD, MPH, Edward L. Peterson,

Lieuwe D. Bos, MSc, PhD, Peter J. Sterk, MD, PhD, Stephen J

Validation of the Pregnancy Asthma Control Test

Physician needs in health informatics: Just ask the docs

Ganesa Wegienka, PhD, Suzanne Havstad, MA, Edward M

Peter M. Wolfgram, MD, David B. Allen, MD

William J. Calhoun, MD, Tmirah Haselkorn, PhD, Dave P

Sequencing the IL4 locus in African Americans implicates rare noncoding variants in asthma susceptibility Gabe Haller, BA, Dara G. Torgerson, PhD, Carole.

Jewlya Lynn, PhD, Sophie Oppenheimer, MS, MPH, Lorena Zimmer, MA

Cosmopolitan and ethnic-specific replication of genetic risk factors for asthma in 2 Latino populations Joshua M. Galanter, MD, Dara Torgerson, PhD,

Reply Journal of Allergy and Clinical Immunology

Roles of arginase variants, atopy, and ozone in childhood asthma

Time for a paradigm shift in asthma treatment: From relieving bronchospasm to controlling systemic inflammation Leif Bjermer, MD Journal of Allergy.

What are the best outcome measurements for atopic eczema

Food allergy: A review and update on epidemiology, pathogenesis, diagnosis, prevention, and management Scott H. Sicherer, MD, Hugh A. Sampson, MD Journal.

Biosimilars and drug development in allergic and immunologic diseases

Comparison of asthma prevalence among African American teenage youth attending public high schools in rural Georgia and urban Detroit Dennis R. Ownby,

Daphne Koinis-Mitchell, PhD, Timothy Craig, DO, Cynthia A

Factors associated with degree of atopy in Latino children in a nationwide pediatric sample: The Genes-environments and Admixture in Latino Asthmatics.

A cluster-randomized trial shows telephone peer coaching for parents reduces children's asthma morbidity Jane M. Garbutt, MB, ChB, Yan Yan, MD, PhD,

Peter Vadas, MD, PhD, Boris Perelman, PhD, Gary Liss, MD, MS

What is an “eosinophilic phenotype” of asthma?

Christine L. M. Joseph, PhD, Dennis R. Ownby, MD, Suzanne L

Cephalosporin Side Chain Cross-reactivity

H. William Kelly, PharmD Journal of Allergy and Clinical Immunology

Personalized asthma therapy in blacks—the role of genetic ancestry

Autophagy: Nobel Prize 2016 and allergy and asthma research

Higher incidence of pediatric anaphylaxis in northern areas of the United States William J. Sheehan, MD, Dionne Graham, PhD, Lin Ma, MS, Sachin Baxi,

Food allergy: Epidemiology, pathogenesis, diagnosis, and treatment

ALOX5AP and LTA4H polymorphisms modify augmentation of bronchodilator responsiveness by leukotriene modifiers in Latinos Haig Tcheurekdjian, MD, Marc.

Geographic variability in childhood asthma prevalence in Chicago

A single intervention for cockroach control reduces cockroach exposure and asthma morbidity in children Felicia A. Rabito, PhD, MPH, John C. Carlson,

Suzanne Havstad, MA, Ganesa Wegienka, PhD, Edward M

Susan A. Rudders, MD, Sarah A. Arias, PhD, Carlos A

Martin Brasholt, MD, Florent Baty, PhD, Hans Bisgaard, MD, DMSci

Reply Journal of Allergy and Clinical Immunology

National prevalence and risk factors for food allergy and relationship to asthma: Results from the National Health and Nutrition Examination Survey

Jessica H. Savage, MD, MHS, Elizabeth C. Matsui, MD, MHS, Robert A

Breast-feeding, aeroallergen sensitization, and environmental exposures during infancy are determinants of childhood allergic rhinitis Christopher D.

Kei E. Fujimura, PhD, Christine C. Johnson, PhD, Dennis R

Edith Chen, PhD, Madeleine U. Shalowitz, MD, Rachel E

Asthma: The past, future, environment, and costs

Asthma Control Test: Reliability, validity, and responsiveness in patients not previously followed by asthma specialists Michael Schatz, MD, MS, Christine.

Environmental factors and eosinophilic esophagitis

Safety and efficacy of repeated monthly carboplatin desensitization

Natural history of cow’s milk allergy

Primary prevention of asthma and allergy

Presentation transcript:

Differences in allergic sensitization by self-reported race and genetic ancestry James J. Yang, PhD, Esteban G. Burchard, MD, MPH, Shweta Choudhry, PhD, Christine C. Johnson, PhD, MPH, Dennis R. Ownby, MD, David Favro, BA, Justin Chen, BS, Matthew Akana, BA, Connie Ha, BS, Pui-Yan Kwok, MD, PhD, Richard Krajenta, BS, Suzanne L. Havstad, MS, Christine L. Joseph, PhD, Max A. Seibold, BA, Mark D. Shriver, PhD, L. Keoki Williams, MD, MPH Journal of Allergy and Clinical Immunology Volume 122, Issue 4, Pages 820-827.e9 (October 2008) DOI: 10.1016/j.jaci.2008.07.044 Copyright © 2008 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Individual admixture estimates for the 385 participants who reported being African American (A) and for the 216 participants who reported being white (B). Each patient number (column) comprises an individual and their admixture, where gray represents African ancestry and blue represents European ancestry. Journal of Allergy and Clinical Immunology 2008 122, 820-827.e9DOI: (10.1016/j.jaci.2008.07.044) Copyright © 2008 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 2 Distribution of study participants within the city limits of Detroit (also includes Hamtramck and Highland Park shown with bolded outlines). Participants who reported being African American are shown against the proportion of individuals within each census tract who reported being African American (A), and participants who reported being white are shown against the proportion of individuals within each census tract who reported being white (B). Census tract proportions are taken from year 2000 US Census data. Journal of Allergy and Clinical Immunology 2008 122, 820-827.e9DOI: (10.1016/j.jaci.2008.07.044) Copyright © 2008 American Academy of Allergy, Asthma & Immunology Terms and Conditions