Example of pretreatment (A and B) and 8-week posttreatment (C and D) PET CT images. Example of pretreatment (A and B) and 8-week posttreatment (C and D)

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Presentation transcript:

Example of pretreatment (A and B) and 8-week posttreatment (C and D) PET CT images. Example of pretreatment (A and B) and 8-week posttreatment (C and D) PET CT images. An early metabolic response is noted in a dominant left hepatic metastasis. E, axial contrast-enhanced CT image obtained at baseline demonstrates a solitary heterogeneous hypodense lesion in segment II of the liver, consistent with a metastatic deposit. F, axial contrast-enhanced CT obtained 4 months after treatment demonstrates slight increase in the lesions with interval decrease in density (from 40 HU to 19 HU, approximately 50%), consistent with treatment effect. The increase in size represents pseudoprogression. G and H, follow-up CT scans obtained 6 and 36 months after the start of treatment demonstrate gradual decrease in size of the metastatic deposit. F. Stephen Hodi et al. Cancer Immunol Res 2014;2:632-642 ©2014 by American Association for Cancer Research