Team Effort by TRAPP Forces a Nucleotide Fumble

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Team Effort by TRAPP Forces a Nucleotide Fumble Ryan M. Nottingham, Suzanne R. Pfeffer Cell Volume 133, Issue 7, Pages 1141-1143 (June 2008) DOI: 10.1016/j.cell.2008.06.012 Copyright © 2008 Elsevier Inc. Terms and Conditions

Figure 1 Multiple TRAPPI Subunits Promote Nucleotide Release from Ypt1p Model of the TRAPPI subassembly in complex with the Ypt1p GTPase (yellow). The pseudo wedge of Bet3p (purple) can be seen pointing into Ypt1p's nucleotide-binding pocket (enlargement at right). Note how multiple subunits hold Ypt1p open to enhance nucleotide release. Cell 2008 133, 1141-1143DOI: (10.1016/j.cell.2008.06.012) Copyright © 2008 Elsevier Inc. Terms and Conditions