Pedram Gerami, Susan S. Jewell, Pedram Pouryazdanparast, Jeffery D

Slides:



Advertisements
Similar presentations
Measurement of Relative Copy Number of CDKN2A/ARF and CDKN2B in Bladder Cancer by Real-Time Quantitative PCR and Multiplex Ligation-Dependent Probe Amplification.
Advertisements

Nine Novel Germline Gene Variants in the RET Proto-Oncogene Identified in Twelve Unrelated Cases Syed A. Ahmed, Karen Snow-Bailey, W. Edward Highsmith,
Development of a Novel One-Tube Isothermal Reverse Transcription Thermophilic Helicase-Dependent Amplification Platform for Rapid RNA Detection James Goldmeyer,
CyclinD1/CyclinD3 Ratio by Real-Time PCR Improves Specificity for the Diagnosis of Mantle Cell Lymphoma Carol D. Jones, Katherine H. Darnell, Roger A.
Quantification of Parvovirus B19 DNA Using COBAS AmpliPrep Automated Sample Preparation and LightCycler Real-Time PCR Stefan Schorling, Gunnar Schalasta,
Design and Multiseries Validation of a Web-Based Gene Expression Assay for Predicting Breast Cancer Recurrence and Patient Survival Ryan K. Van Laar The.
Accurate Molecular Characterization of Formalin-Fixed, Paraffin-Embedded Tissues by microRNA Expression Profiling Anna E. Szafranska, Timothy S. Davison,
Enterococcus faecalis Induces Inflammatory Bowel Disease in Interleukin-10 Knockout Mice Edward Balish, Thomas Warner The American Journal of Pathology.
Duplex Ratio Tests as Diagnostic Biomarkers in Malignant Melanoma
A Genome-Wide High-Resolution Array-CGH Analysis of Cutaneous Melanoma and Comparison of Array-CGH to FISH in Diagnostic Evaluation  Lu Wang, Mamta Rao,
Genes with Bimodal Expression Are Robust Diagnostic Targets that Define Distinct Subtypes of Epithelial Ovarian Cancer with Different Overall Survival 
Statistical Considerations for Immunohistochemistry Panel Development after Gene Expression Profiling of Human Cancers  Rebecca A. Betensky, Catherine.
Vida Kocbek, Katja Vouk, Nick A. Bersinger, Michael D
In Silico Proficiency Testing for Clinical Next-Generation Sequencing
Laboratory Guidelines for Detection, Interpretation, and Reporting of Maternal Cell Contamination in Prenatal Analyses  Narasimhan Nagan, Nicole E. Faulkner,
The Spectrum of CFTR Variants in Nonwhite Cystic Fibrosis Patients
Eligibility Criteria and Genetic Testing Results from a High-Risk Cohort for Hereditary Breast and Ovarian Cancer Syndrome in Southeastern Ontario  Ricardo.
Molecular Testing Guideline for Selection of Lung Cancer Patients for EGFR and ALK Tyrosine Kinase Inhibitors  Neal I. Lindeman, Philip T. Cagle, Mary.
TERT and AURKA Gene Copy Number Gains Enhance the Detection of Acral Lentiginous Melanomas by Fluorescence in Situ Hybridization  Alba Diaz, Joan Anton.
Molecular Genetics of Pediatric Soft Tissue Tumors
Da Eun Lee, Ji Hyae Lim, Min Hyoung Kim, So Yeon Park, Hyun Mee Ryu 
Somatic Mutations of PI3K in Early and Advanced Gallbladder Cancer
Mutation Screening in Juvenile Polyposis Syndrome
Maria J. Worsham, Sandra R. Wolman, Richard J. Zarbo 
Joanna Wang, Chetan Bettegowda  The Journal of Molecular Diagnostics 
Increased Sensitivity of the Roche COBAS AMPLICOR HCV Test, Version 2
Design and Multiseries Validation of a Web-Based Gene Expression Assay for Predicting Breast Cancer Recurrence and Patient Survival  Ryan K. Van Laar 
A Novel Streptococcus Organism Identified in a Case of Fulminant Endocarditis Using 16S rDNA Sequencing  Zsolt Jobbagy, Claire B. Fabian, Vincent A. Memoli,
A Lean Laboratory The Journal of Molecular Diagnostics
ALK Status Testing in Non–Small Cell Lung Carcinoma
The History and Impact of Molecular Coding Changes on Coverage and Reimbursement of Molecular Diagnostic Tests  Susan J. Hsiao, Mahesh M. Mansukhani,
Prevalence of Human Papillomavirus Infection in Unselected SurePath Samples Using the APTIMA HPV mRNA Assay  Matejka Rebolj, Sarah Preisler, Ditte M.
Getting Things Backwards to Prevent Primer Dimers
Patrick R. Murray  The Journal of Molecular Diagnostics 
Chronic Myeloid Leukemia
William L. Gerald, M.D., Ph.D, 1954–2008
A Genome-Wide High-Resolution Array-CGH Analysis of Cutaneous Melanoma and Comparison of Array-CGH to FISH in Diagnostic Evaluation  Lu Wang, Mamta Rao,
Development of an NPM1/MLF1 D-FISH Probe Set for the Detection of t(3;5)(q25;q35) Identified in Patients with Acute Myeloid Leukemia  Umut Aypar, Ryan.
Chromosomal Biomarkers for Detection of Human Papillomavirus Associated Genomic Instability in Epithelial Cells of Cervical Cytology Specimens  Irina.
Evaluation of BRAF Mutation Testing Methodologies in Formalin-Fixed, Paraffin- Embedded Cutaneous Melanomas  Johanne Lade-Keller, Kirsten M. Rømer, Per.
Next-Generation Sequencing for Simultaneous Determination of Human Papillomavirus Load, Subtype, and Associated Genomic Copy Number Changes in Tumors 
Diagnosis of BK Viral Nephropathy in the Renal Allograft Biopsy
Christine Formisano-Tréziny, Marina de San Feliciano, Jean Gabert 
BRAF Mutation Testing in Solid Tumors
Skin Biopsy Is a Practical Approach for the Clinical Diagnosis and Molecular Genetic Analysis of X-Linked Alport's Syndrome  Fang Wang, Dan Zhao, Jie.
Duplex Ratio Tests as Diagnostic Biomarkers in Malignant Melanoma
Multiplex Bead Suspension Array for Screening Neisseria gonorrhoeae Antibiotic Resistance Genetic Determinants in Noncultured Clinical Samples  Sergey.
The Molecular Pathology of Primary Immunodeficiencies
Report of New Haplotype for ABCC2 Gene
Vida Kocbek, Katja Vouk, Nick A. Bersinger, Michael D
Chromosomal Abnormalities in Non-Small Cell Lung Carcinomas and in Bronchial Epithelia of High-Risk Smokers Detected by Multi-Target Interphase Fluorescence.
Retrospective Comparison of Nucleic Acid Sequence–Based Amplification, Real-Time PCR, and Galactomannan Test for Diagnosis of Invasive Aspergillosis 
Next-Generation Sequencing for Infectious Disease Diagnosis and Management  Martina I. Lefterova, Carlos J. Suarez, Niaz Banaei, Benjamin A. Pinsky  The.
Long Polymerase Chain Reaction-Based Fluorescence in Situ Hybridization Analysis of Female Carriers of X-Linked Chronic Granulomatous Disease Deletions 
Ayalew Tefferi, Pierre Noel, Curtis A. Hanson 
Erratum The American Journal of Human Genetics
Inherited Cardiomyopathies
Diagnosis of BK Viral Nephropathy in the Renal Allograft Biopsy
Society for Investigative Dermatology 2010 Meeting Minutes
Use of Pyrosequencing of 16S rRNA Fragments to Differentiate between Bacteria Responsible for Neonatal Sepsis  Jeanne A. Jordan, Allyson R. Butchko, Mary.
Karen Snow-Bailey, Ph.D., 1961–2006
Jie Hu, Malini Sathanoori, Sally J. Kochmar, Urvashi Surti 
Circulating Tumor Cells and Detection of the Melanoma-Associated Antigen HMW-MAA in the Serum of Melanoma Patients  Anja Ulmer, Gerhard Fierlbeck  Journal.
Journal of Investigative Dermatology
Varying Mutational Alterations in Multiple Primary Melanomas
86. A Highly Compact Epitope-Based Marker Suicide Gene for Safer and Easier Adoptive T-Cell Gene Therapy    Molecular Therapy  Volume 20, Pages S35-S36.
Clinical Experience with the Cervista HPV HR Assay
Angiotensin I-Converting Enzyme
Monique A. Johnson, Marvin J. Yoshitomi, C. Sue Richards 
The History and Impact of Molecular Coding Changes on Coverage and Reimbursement of Molecular Diagnostic Tests  Susan J. Hsiao, Mahesh M. Mansukhani,
Presentation transcript:

Copy Number Gains in 11q13 and 8q34 Are Highly Linked to Prognosis in Cutaneous Malignant Melanoma  Pedram Gerami, Susan S. Jewell, Pedram Pouryazdanparast, Jeffery D. Wayne, Zahra Haghighat, Klaus J. Busam, Alfred Rademaker, Larry Morrison  The Journal of Molecular Diagnostics  Volume 13, Issue 3, Pages 352-358 (May 2011) DOI: 10.1016/j.jmoldx.2011.01.011 Copyright © 2011 American Society for Investigative Pathology and the Association for Molecular Pathology Terms and Conditions

Figure 1 A: FISH image with the spectrum green fluorochrome showing melanoma with prominent gains in 11q13 (CCND1) (original magnification, ×1000). B: FISH image with the spectrum red fluorochrome showing melanoma with prominent gains in 8q34 (MYC) (original magnification, ×1000). The Journal of Molecular Diagnostics 2011 13, 352-358DOI: (10.1016/j.jmoldx.2011.01.011) Copyright © 2011 American Society for Investigative Pathology and the Association for Molecular Pathology Terms and Conditions