Cross-sectional DXA and MR measures of tibial periarticular bone associate with radiographic knee osteoarthritis severity G.H. Lo, A.M. Tassinari, J.B.

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Cross-sectional DXA and MR measures of tibial periarticular bone associate with radiographic knee osteoarthritis severity G.H. Lo, A.M. Tassinari, J.B. Driban, L.L. Price, E. Schneider, S. Majumdar, T.E. McAlindon Osteoarthritis and Cartilage Volume 20, Issue 7, Pages 686-693 (July 2012) DOI: 10.1016/j.joca.2012.03.006 Copyright © 2012 Terms and Conditions

Fig. 1 Trabecular magnetic resonance image of a knee with medial tibiofemoral OA JSN grade 3. Marrow fat appears white (high-intensity signal) while bone appears black (no signal). The white rectangle is a sample ROI. Osteoarthritis and Cartilage 2012 20, 686-693DOI: (10.1016/j.joca.2012.03.006) Copyright © 2012 Terms and Conditions

Fig. 2 DXA of the same knee scanned in Fig. 1 with medial tibiofemoral OA with JSN grade 3. The red rectangle bounded by the yellow bone border is the ROI used to measure the medial tibial paBMD. Osteoarthritis and Cartilage 2012 20, 686-693DOI: (10.1016/j.joca.2012.03.006) Copyright © 2012 Terms and Conditions

Fig. 3 Scatter plots (N = 482) of the proximal medial tibial paBMD (g/cm2) determined by DXA, versus MRI measured (a) the tibial apparent bone volume fraction (aBV/TV), (b) the apparent trabecular number (aTb.N) (1/mm), (c) apparent trabecular thickness (aTb.Th) (mm), (d) the apparent trabecular spacing (aTb.Sp) (mm). The points are color coded to the knee medial JSN scores. Osteoarthritis and Cartilage 2012 20, 686-693DOI: (10.1016/j.joca.2012.03.006) Copyright © 2012 Terms and Conditions

Fig. 4 Whisker plots with notches by medial JSN score of (a) proximal medial tibial paBMD, (b) apparent bone volume fraction (aBV/TV), (c) apparent trabecular number (aTb.N) (1/mm), (d) apparent trabecular thickness (aTb.Th) (mm), and (e) apparent trabecular spacing (aTb.Sp) (mm). Values above whisker plots are median values in the respective medial JSN groups. ∗Denotes statistically significant difference (P < 0.05) compared to the referent group, knees with a medial JSN score = 0. Osteoarthritis and Cartilage 2012 20, 686-693DOI: (10.1016/j.joca.2012.03.006) Copyright © 2012 Terms and Conditions