Diagnostic and Therapeutic Advances in Blastic Plasmacytoid Dendritic Cell Neoplasm: A Focus on Hematopoietic Cell Transplantation Mohamed A. Kharfan-Dabaja,

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Presentation transcript:

Diagnostic and Therapeutic Advances in Blastic Plasmacytoid Dendritic Cell Neoplasm: A Focus on Hematopoietic Cell Transplantation Mohamed A. Kharfan-Dabaja, Hillard M. Lazarus, Taiga Nishihori, Rami A. Mahfouz, Mehdi Hamadani Biology of Blood and Marrow Transplantation Volume 19, Issue 7, Pages 1006-1012 (July 2013) DOI: 10.1016/j.bbmt.2013.01.027 Copyright © 2013 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 (A) Punch biopsy of a skin lesion in a patient with BPDCN showing a striking diffuse infiltrate of atypical mononuclear cells with round to oval nuclei and scant cytoplasm throughout the papillary and superficial reticular dermis (H&E staining). Immunohistochemical staining showing expression of CD4 (B) and CD56 (C) on malignant cells. (Parts A and B reproduced from Hamadani M, Magro CM, Porcu P. CD4+ CD56+ hematodermic tumor [plasmacytoid dendritic cell neoplasm]. Br J Haematol 2008;140:122, with permission from ©John Wiley and Sons [license number: 3034330839698]. All rights reserved.) Biology of Blood and Marrow Transplantation 2013 19, 1006-1012DOI: (10.1016/j.bbmt.2013.01.027) Copyright © 2013 American Society for Blood and Marrow Transplantation Terms and Conditions