Guy Shalom, MD, MHA, Elena Kahn, MD, Sima Halevy, MD JAAD Case Reports

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A severe fatal case of Darier-White disease—an extreme phenotype or a new entity? Guy Shalom, MD, MHA, Elena Kahn, MD, Sima Halevy, MD JAAD Case Reports Volume 1, Issue 1, Pages 41-43 (January 2015) DOI: 10.1016/j.jdcr.2014.11.002 Copyright © 2014 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 Progressive deterioration of 20 years' duration. The patient in 1999, 2005, and 2013. JAAD Case Reports 2015 1, 41-43DOI: (10.1016/j.jdcr.2014.11.002) Copyright © 2014 American Academy of Dermatology, Inc. Terms and Conditions

Fig 2 The 2013 DWD episode. Note the filiform keratoderma. JAAD Case Reports 2015 1, 41-43DOI: (10.1016/j.jdcr.2014.11.002) Copyright © 2014 American Academy of Dermatology, Inc. Terms and Conditions

Fig 3 DWD: giant comedons, 2005; cachexia and erythema, 2005; compared with 2013. JAAD Case Reports 2015 1, 41-43DOI: (10.1016/j.jdcr.2014.11.002) Copyright © 2014 American Academy of Dermatology, Inc. Terms and Conditions

Fig 4 Skin biopsy photomicrograph shows evidence of keratotic plug, dyskeratosis, and corps ronds (arrows). (H&E stain, original magnification: ×360). JAAD Case Reports 2015 1, 41-43DOI: (10.1016/j.jdcr.2014.11.002) Copyright © 2014 American Academy of Dermatology, Inc. Terms and Conditions