Treating Obesity? It's in the Bag!

Slides:



Advertisements
Similar presentations
Individualized Medicine from Prewomb to Tomb Eric J. Topol Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell Copyright.
Advertisements

What We Talk About When We Talk About Fat Evan D. Rosen, Bruce M. Spiegelman Cell Volume 156, Issue 1, Pages (January 2014) DOI: /j.cell
Mitoconfusion: Noncanonical Functioning of Dynamism Factors in Static Mitochondria of the Heart Moshi Song, Gerald W. Dorn Cell Metabolism Volume 21, Issue.
Maintaining Cell Identity through Global Control of Genomic Organization Gioacchino Natoli Immunity Volume 33, Issue 1, Pages (July 2010) DOI: /j.immuni
Making Proteins in the Powerhouse B. Martin Hällberg, Nils-Göran Larsson Cell Metabolism Volume 20, Issue 2, Pages (August 2014) DOI: /j.cmet
Distribution of Human Embryonic Stem Cell Lines: Who, When, and Where Jennifer B. McCormick, Jason Owen-Smith, Christopher Thomas Scott Cell Stem Cell.
Xenobiotics Shape the Physiology and Gene Expression of the Active Human Gut Microbiome Corinne Ferrier Maurice, Henry Joseph Haiser, Peter James Turnbaugh.
Cancer Metabolism Cell Volume 148, Issue 3, (February 2012) DOI: /j.cell Copyright © 2012 Terms and Conditions Terms and Conditions.
Functions of mitochondrial ISCU and cytosolic ISCU in mammalian iron-sulfur cluster biogenesis and iron homeostasis Wing-Hang Tong, Tracey A. Rouault Cell.
PTEN Loss in the Myf5 Lineage Redistributes Body Fat and Reveals Subsets of White Adipocytes that Arise from Myf5 Precursors Joan Sanchez-Gurmaches, Chien-Min.
Nuclear Receptors, RXR, and the Big Bang Ronald M. Evans, David J. Mangelsdorf Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell
Human Brown Adipose Tissue Sven Enerbäck Cell Metabolism Volume 11, Issue 4, Pages (April 2010) DOI: /j.cmet Copyright © 2010.
The Metabolic Basis of Pulmonary Arterial Hypertension Gopinath Sutendra, Evangelos D. Michelakis Cell Metabolism Volume 19, Issue 4, Pages (April.
Lipin-1 Regulates Autophagy Clearance and Intersects with Statin Drug Effects in Skeletal Muscle Peixiang Zhang, M. Anthony Verity, Karen Reue Cell Metabolism.
Germline Energetics, Aging, and Female Infertility Jonathan L. Tilly, David A. Sinclair Cell Metabolism Volume 17, Issue 6, Pages (June 2013) DOI:
Oxygen Sensors at the Crossroad of Metabolism Julián Aragonés, Peter Fraisl, Myriam Baes, Peter Carmeliet Cell Metabolism Volume 9, Issue 1, Pages
One Strike against Low-Carbohydrate Diets
Volume 14, Issue 2, Pages (August 2011)
Ghrelin—a new player in glucose homeostasis?
Jochen G. Schneider, Joseph H. Nadeau  Cell Metabolism 
Novel SIRT1 Mutation Linked to Autoimmune Diabetes in Humans
“Corination” of the proANP converting enzyme
Bariatric Surgery Restores Gut-Brain Signaling to Reduce Fat Intake
Accelerating drug discovery: Open source cancer cell biology?
Boosting Bacterial Metabolism to Combat Antibiotic Resistance
Does Hypothalamic Inflammation Cause Obesity?
Omega 3 Fatty Acids and GPR120
Pancreatic β cells: Responding to the matrix
Serotonin and the Orchestration of Energy Balance
Volume 12, Issue 5, Pages (November 2010)
Volume 24, Issue 3, Pages (September 2016)
Antibiotic Exposure Promotes Fat Gain
Getting to the heart of COX-2 inhibition
Gal3 Links Inflammation and Insulin Resistance
Volume 15, Issue 1, Pages (January 2012)
The Cardiovascular Biology of Glucagon-like Peptide-1
Is Predisposition to NAFLD and Obesity Communicable?
Getting to the heart of COX-2 inhibition
Michael Downes, Christopher Liddle  Cell Metabolism 
Independent Control of Aging and Axon Regeneration
Volume 26, Issue 1, Pages 6-7 (July 2017)
The CAMplexities of Central Ghrelin
Adiponectin Sparks an Interest in Calcium
One Strike against Low-Carbohydrate Diets
Why We Should Put Clothes on Mice
Autophagy: A Sweet Process in Diabetes
IL-6 Muscles In on the Gut and Pancreas to Enhance Insulin Secretion
Branching Out for Detection of Type 2 Diabetes
Modifying Mitochondrial tRNAs: Delivering What the Cell Needs
Lasker Lauds Leptin Cell Metabolism
Volume 24, Issue 4, Pages (October 2016)
Exercise Controls Non-Coding RNAs
Volume 30, Issue 2, Pages (February 2009)
The Cardiovascular Biology of Glucagon-like Peptide-1
Hold the Door: Role of the Gut Barrier in Diabetes
Treating obesity: Does antagonism of NPY fit the bill?
Volume 14, Issue 2, Pages (August 2011)
Adipose Dendritic Cells Come Out of Hiding
An IRKO in the Podo: Impaired Insulin Signaling in Podocytes and the Pathogenesis of Diabetic Nephropathy  Susan B. Gurley, Thomas M. Coffman  Cell Metabolism 
Oxytocin: The Neuropeptide of Love Reveals Some of Its Secrets
Role reversal: Brain insulin and liver STAT3
Unlikely partners in weight loss?
Immune Cells Exploit a Neural Circuit to Enter the CNS
Hap1 and GABA: Thinking about food intake
Macrophage Metabolism Shapes Angiogenesis in Tumors
Volume 5, Issue 1, Pages 5-6 (January 2007)
Tipping the Energy Balance toward Longevity
AMPK and p53 help cells through lean times
Estrogens and Obesity: Is It All in Our Heads?
Obesity Genes—It's All About the Parents!
Presentation transcript:

Treating Obesity? It's in the Bag! Anthony P. Coll  Cell Metabolism  Volume 11, Issue 2, Pages 95-96 (February 2010) DOI: 10.1016/j.cmet.2010.01.006 Copyright © 2010 Elsevier Inc. Terms and Conditions

Figure 1 Activation of BRS-3 Causes Weight Loss Bag-1 is a potent agonist at BRS-3, a receptor highly expressed within the CNS. The pathways responsible for the anorexigenic effects of this ligand remain to be fully elucidated but may involve multiple regions of the brain as well as the gut. Cell Metabolism 2010 11, 95-96DOI: (10.1016/j.cmet.2010.01.006) Copyright © 2010 Elsevier Inc. Terms and Conditions