Volume 2, Issue 6, Pages (November 2016)

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Volume 2, Issue 6, Pages 439-441 (November 2016) Metastatic melanoma with spontaneous complete regression of a thick primary lesion Hasan Khosravi, BS, Andressa L. Akabane, MD, Allireza Alloo, MD, Rosalynn M. Nazarian, MD, Genevieve M. Boland, MD, PhD JAAD Case Reports Volume 2, Issue 6, Pages 439-441 (November 2016) DOI: 10.1016/j.jdcr.2016.09.011 Copyright © 2016 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 Left side of the chest skin biopsy for primary malignant melanoma. Histopathologic examination found a thick primary melanoma characterized by atypical pigmented epithelioid cells with extensive ulceration. (Hematoxylin-eosin stain; original magnification: ×100.) JAAD Case Reports 2016 2, 439-441DOI: (10.1016/j.jdcr.2016.09.011) Copyright © 2016 American Academy of Dermatology, Inc. Terms and Conditions

Fig 2 Clinical photograph of the primary melanoma on the left side of the chest 4 weeks after biopsy. The clinically notable pigmented lesion had regressed to a small scaled area of skin. JAAD Case Reports 2016 2, 439-441DOI: (10.1016/j.jdcr.2016.09.011) Copyright © 2016 American Academy of Dermatology, Inc. Terms and Conditions

Fig 3 Histologic evaluation of the site of the primary lesion showed a scar with no residual melanoma identified. (Hematoxylin-eosin stain; original magnification: ×40.) JAAD Case Reports 2016 2, 439-441DOI: (10.1016/j.jdcr.2016.09.011) Copyright © 2016 American Academy of Dermatology, Inc. Terms and Conditions

Fig 4 MRI T1 postcontrast axial image shows more than 100 new enhancing hemorrhagic intracranial metastases throughout the cerebral hemispheres. JAAD Case Reports 2016 2, 439-441DOI: (10.1016/j.jdcr.2016.09.011) Copyright © 2016 American Academy of Dermatology, Inc. Terms and Conditions