Piotr Rzymski, Ph. D. , Przemysław Niedzielski, Ph. D

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Presentation transcript:

Metal accumulation in the human uterus varies by pathology and smoking status Piotr Rzymski, Ph.D., Przemysław Niedzielski, Ph.D., Paweł Rzymski, M.D., Ph.D., Katarzyna Tomczyk, M.D., Lidia Kozak, Ph.D., Barbara Poniedziałek, Ph.D. Fertility and Sterility Volume 105, Issue 6, Pages 1511-1518.e3 (June 2016) DOI: 10.1016/j.fertnstert.2016.02.006 Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

Fertility and Sterility 2016 105, 1511-1518. e3DOI: (10. 1016/j Fertility and Sterility 2016 105, 1511-1518.e3DOI: (10.1016/j.fertnstert.2016.02.006) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

Figure 1 Association between metal levels (median and interquartile range) and histologic image of endometrium in the whole group (white bars) as well as in the subset of never-smokers (gray bars). Asterisks indicate a significant difference (P<.05) from histologically normal endometrial tissue in the corresponding group. Fertility and Sterility 2016 105, 1511-1518.e3DOI: (10.1016/j.fertnstert.2016.02.006) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

Figure 2 Cu/Zn ratio (median and interquartile range) in histologically differentiated (A) endometrial and (B) endocervical tissues in the whole group (white bars) as well as in the subset of never-smokers (gray bars). Asterisks indicate a significant difference (P<.05) from histologically normal endometrial/endocervical tissue in the corresponding group. Concentrations (median and interquartile range) of (C) Cd, (D) Pb, and (E) Ni in endometrium (white bars) and endocervix (gray bars) according to smoking history (NS = never smokers; CS = current smokers; FS = former smokers). Asterisks indicate a significant difference (P<.05) between indicated groups. Fertility and Sterility 2016 105, 1511-1518.e3DOI: (10.1016/j.fertnstert.2016.02.006) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

Figure 3 Association between metal levels (median and interquartile range) and histologic image of endocervix in the whole group (white bars) as well as in the subset of never-smokers (gray bars). Asterisks indicate a significant difference (P<.05) from histologically normal endocervical tissue in the corresponding group. Fertility and Sterility 2016 105, 1511-1518.e3DOI: (10.1016/j.fertnstert.2016.02.006) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions