Yu Shi, Yi-fang Ping, Xia Zhang, Xiu-wu Bian Cell Stem Cell

Slides:

Advertisements

Similar presentations

LSD1 Is a Subunit of the NuRD Complex and Targets the Metastasis Programs in Breast Cancer Yan Wang, Hua Zhang, Yupeng Chen, Yimin Sun, Fen Yang, Wenhua.

Advertisements

Individualized Medicine from Prewomb to Tomb Eric J. Topol Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell Copyright.

What We Talk About When We Talk About Fat Evan D. Rosen, Bruce M. Spiegelman Cell Volume 156, Issue 1, Pages (January 2014) DOI: /j.cell

Distinct Self-Renewal and Differentiation Phases in the Niche of Infrequently Dividing Hair Follicle Stem Cells Ying V. Zhang, Janice Cheong, Nichita Ciapurin,

Maintaining Cell Identity through Global Control of Genomic Organization Gioacchino Natoli Immunity Volume 33, Issue 1, Pages (July 2010) DOI: /j.immuni

Bone Marrow-Derived Cell Therapy Stimulates Endogenous Cardiomyocyte Progenitors and Promotes Cardiac Repair Francesco S. Loffredo, Matthew L. Steinhauser,

Distribution of Human Embryonic Stem Cell Lines: Who, When, and Where Jennifer B. McCormick, Jason Owen-Smith, Christopher Thomas Scott Cell Stem Cell.

Evolution of the Cancer Stem Cell Model Antonija Kreso, John E. Dick Cell Stem Cell Volume 14, Issue 3, Pages (March 2014) DOI: /j.stem

Nuclear Receptors, RXR, and the Big Bang Ronald M. Evans, David J. Mangelsdorf Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell

Module Map of Stem Cell Genes Guides Creation of Epithelial Cancer Stem Cells David J. Wong, Helen Liu, Todd W. Ridky, David Cassarino, Eran Segal, Howard.

IPSC Crowdsourcing: A Model for Obtaining Large Panels of Stem Cell Lines for Screening Mahendra Rao Cell Stem Cell Volume 13, Issue 4, Pages (October.

Fate Restriction and Multipotency in Retinal Stem Cells Lázaro Centanin, Burkhard Hoeckendorf, Joachim Wittbrodt Cell Stem Cell Volume 9, Issue 6, Pages.

Myc Represses Primitive Endoderm Differentiation in Pluripotent Stem Cells Keriayn N. Smith, Amar M. Singh, Stephen Dalton Cell Stem Cell Volume 7, Issue.

Normal and Leukemic Stem Cell Niches: Insights and Therapeutic Opportunities Koen Schepers, Timothy B. Campbell, Emmanuelle Passegué Cell Stem Cell Volume.

Gastrulation Movements: the Logic and the Nuts and Bolts Maria Leptin Developmental Cell Volume 8, Issue 3, Pages (March 2005) DOI: /j.devcel

Quantitative Single-Cell Approaches to Stem Cell Research Martin Etzrodt, Max Endele, Timm Schroeder Cell Stem Cell Volume 15, Issue 5, Pages (November.

Brain Tumors: An Update on Clinical PET Research in Gliomas

Chemotherapy and Cancer Stem Cells

Cutaneous Cancer Stem Cells: β-Catenin Strikes Again

Stress Can Be a Good Thing for Blood Formation

Cancer: Inappropriate Expression of Stem Cell Programs?

Back to 2D Culture for Ground State of Intestinal Stem Cells

The Tailless Root of Glioma: Cancer Stem Cells

Finding Shangri-La: Limiting the Impact of Senescence on Aging

9-1-1: HSCs Respond to Emergency Calls

Volume 1, Issue 1, Pages (June 2007)

Cell Cycle Rules Pluripotency

The LUNGe to Model Alveolar Lung Diseases in a Dish

A Path to Insulin Independence: “The End of the Beginning”

Volume 9, Issue 2, Pages (August 2011)

Some DCs Are “B”etter Immunity

Blocking HIF1α Activity Eliminates Hematological Cancer Stem Cells

Anselme Perrier, Marc Peschanski Cell Stem Cell

The aCCR(2)ual of M2 Macrophages Provides Some Breathing Room

MSCs, Macrophages, and Cancer: A Dangerous Ménage-à-Trois

Volume 26, Issue 1, Pages 1-2 (July 2014)

Neural Circuits Serve as Periscopes for NSCs

Regulating Cancer Stem Cells the miR Way

Wing Y. Chang, William L. Stanford Cell Stem Cell

A New Image of the Hematopoietic Stem Cell Vascular Niche

Stem Cell Therapies in Clinical Trials: Progress and Challenges

Modeling the Glomerular Filtration Barrier: Are You Kidney-ing Me?

Cutaneous Cancer Stem Cells: β-Catenin Strikes Again

TRRAP and the Maintenance of Stemness in Gliomas

MicroRNA Regulation of Stem Cell Fate

Blocking HIF1α Activity Eliminates Hematological Cancer Stem Cells

MicroRNAs and Parallel Stem Cell Lives

Integrin Alpha 6: Anchors Away for Glioma Stem Cells

Early Embryos Reprogram DNA Methylation in Two Steps

The aCCR(2)ual of M2 Macrophages Provides Some Breathing Room

Secretion of Shh by a Neurovascular Bundle Niche Supports Mesenchymal Stem Cell Homeostasis in the Adult Mouse Incisor Hu Zhao, Jifan Feng, Kerstin Seidel,

Tumor Self-Seeding: Bidirectional Flow of Tumor Cells

Meddling with METTLs in Normal and Leukemia Stem Cells

Frances Balkwill, Kellie A. Charles, Alberto Mantovani Cancer Cell

Volume 21, Issue 1, Pages (July 2017)

Powering Reprogramming with Vitamin C

NO Signals from the Cancer Stem Cell Niche

Direct Conversion Provides Old Neurons from Aged Donor’s Skin

Ann Marie Schmidt, Kathryn J. Moore Cell Metabolism

Selfish Stem Cells Compete with Each Other

The Side Story of Stem-like Glioma Cells

Volume 22, Issue 4, Pages (April 2018)

The Tailless Root of Glioma: Cancer Stem Cells

Volume 23, Issue 6, Pages (December 2018)

The Tropism of Pleiotrophin: Orchestrating Glioma Brain Invasion

Using Notches to Track Mammary Epithelial Cell Homeostasis

Some DCs Are “B”etter Immunity

Macrophage Metabolism Shapes Angiogenesis in Tumors

Mesp1 at the Heart of Mesoderm Lineage Specification

Volume 17, Issue 2, Pages (February 2010)

Presentation transcript:

Hostile Takeover: Glioma Stem Cells Recruit TAMs to Support Tumor Progression Yu Shi, Yi-fang Ping, Xia Zhang, Xiu-wu Bian Cell Stem Cell Volume 16, Issue 3, Pages 219-220 (March 2015) DOI: 10.1016/j.stem.2015.02.008 Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure 1 Glioma Stem Cells Recruit Monocyte-Derived Tumor-Associated Macrophages to Promote Glioblastoma Tumor Growth (A) Glioma stem cells (GSCs) in perivascular niches secrete Periostin (POSTN) to attract circulating monocytes. (B) The emigration and differentiation of recruited monocytes in GSC niches. (C) POSTN maintains M2 tumor-associated macrophages (TAMs) that promote tumor growth. (D) Targeting POSTN or GSCs attenuates the recruitment of M2 TAMs and halts glioblastoma (GBM) tumor progression. Cell Stem Cell 2015 16, 219-220DOI: (10.1016/j.stem.2015.02.008) Copyright © 2015 Elsevier Inc. Terms and Conditions