Magnetic Resonance vs Transient Elastography Analysis of Patients With Nonalcoholic Fatty Liver Disease: A Systematic Review and Pooled Analysis of Individual.

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Magnetic Resonance vs Transient Elastography Analysis of Patients With Nonalcoholic Fatty Liver Disease: A Systematic Review and Pooled Analysis of Individual Participants Cynthia Hsu, Cyrielle Caussy, Kento Imajo, Jun Chen, Siddharth Singh, Kellee Kaulback, Minh-Da Le, Jonathan Hooker, Xin Tu, Ricki Bettencourt, Meng Yin, Claude B. Sirlin, Richard L. Ehman, Atsushi Nakajima, Rohit Loomba Clinical Gastroenterology and Hepatology Volume 17, Issue 4, Pages 630-637.e8 (March 2019) DOI: 10.1016/j.cgh.2018.05.059 Copyright © 2019 AGA Institute Terms and Conditions

Figure 1 Distribution of liver stiffness measurements by (A) transient elastography and (B) magnetic resonance (MR) elastography. Clinical Gastroenterology and Hepatology 2019 17, 630-637.e8DOI: (10.1016/j.cgh.2018.05.059) Copyright © 2019 AGA Institute Terms and Conditions

Figure 2 Diagnostic accuracy of transient elastography and magnetic resonance (MR) elastography for diagnosing dichotomized stages of fibrosis. AUROC, area under the receiver-operating characteristic curve. Clinical Gastroenterology and Hepatology 2019 17, 630-637.e8DOI: (10.1016/j.cgh.2018.05.059) Copyright © 2019 AGA Institute Terms and Conditions

Figure 3 Distribution of thresholds value for the diagnosis of dichotomized fibrosis stage of (A) transient elastography and (B) magnetic resonance (MR) elastography. The lower line corresponds to the thresholds for a fixed sensitivity at 90%, line in the middle corresponds to the optimal threshold and the upper line corresponds to the thresholds for a fixed specificity at 90%. Clinical Gastroenterology and Hepatology 2019 17, 630-637.e8DOI: (10.1016/j.cgh.2018.05.059) Copyright © 2019 AGA Institute Terms and Conditions

Figure 4 Magnetic resonance elastography (MRE) and transient elastography (TE) images from representative patients with stage 0, 1, 2, 3, and 4 fibrosis, respectively. Clinical Gastroenterology and Hepatology 2019 17, 630-637.e8DOI: (10.1016/j.cgh.2018.05.059) Copyright © 2019 AGA Institute Terms and Conditions

Supplementary Figure 1 Flow chart summarizing study identification and selection. ARFI, MRE, SWE, TE. Clinical Gastroenterology and Hepatology 2019 17, 630-637.e8DOI: (10.1016/j.cgh.2018.05.059) Copyright © 2019 AGA Institute Terms and Conditions

Supplementary Figure 2 Flow chart summarizing patient exclusion for statistical analysis. MRE, VCTE. Clinical Gastroenterology and Hepatology 2019 17, 630-637.e8DOI: (10.1016/j.cgh.2018.05.059) Copyright © 2019 AGA Institute Terms and Conditions

Supplementary Figure 3 ROC Curve of MRE and TE for the diagnosis of dichotomized stage of fibrosis. Clinical Gastroenterology and Hepatology 2019 17, 630-637.e8DOI: (10.1016/j.cgh.2018.05.059) Copyright © 2019 AGA Institute Terms and Conditions