Levosimendan Reversing Low Output Syndrome After Heart Transplantation

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Presentation transcript:

Levosimendan Reversing Low Output Syndrome After Heart Transplantation Liisa M. Petäjä, MD, Jorma T. Sipponen, MD, PhD, Pekka J. Hämmäinen, MD, PhD, Heidi I. Eriksson, MD, PhD, Markku T. Salmenperä, MD, PhD, Raili T. Suojaranta-Ylinen, MD, PhD The Annals of Thoracic Surgery Volume 82, Issue 4, Pages 1529-1531 (October 2006) DOI: 10.1016/j.athoracsur.2006.02.026 Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Hemodynamics and inotropy. In both graphs the X-axis shows time in hours from the beginning of levosimendan. Top graph: the left Y-axis shows pressure in mm Hg (MAP, PCWP) and percentage (SvO2). The right Y-axis shows L/min/m2 (cardiac index). –– = MAP; ---- = SvO2; —●— = CI; —▼— = PCWP. Bottom graph: the left Y-axis shows doses of infusions of epinephrine and norepinephrine in ng/kg/min. The right Y-axis shows doses of the infusions of milrinone and levosimendan in micrograms/kg/min. –– = epinephrine; -– = milrinone; ---- = norepinephrine; —— = levosimendan. (CI = cardiac index; FIO2 = inspired oxygen fraction; IABP = intraaortic balloon pump; MAP = mean arterial pressure; mRVD = mild right ventricular dysfunction; PCWP = pulmonary capillary wedge pressure; SvO2 = mixed central venous hemoglobin saturation; TTE = transthoracic echocardiography.) The Annals of Thoracic Surgery 2006 82, 1529-1531DOI: (10.1016/j.athoracsur.2006.02.026) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions