Dopexamine attenuates microvascular perfusion injury of the small bowel in pigs induced by extracorporeal circulation F.‐U. Sack, B. Reidenbach, A. Schledt,

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Dopexamine attenuates microvascular perfusion injury of the small bowel in pigs induced by extracorporeal circulation F.‐U. Sack, B. Reidenbach, A. Schledt, R. Dollner, S. Taylor, M.M. Gebhard, S. Hagl British Journal of Anaesthesia Volume 88, Issue 6, Pages 841-847 (June 2002) DOI: 10.1093/bja/88.6.841 Copyright © 2002 British Journal of Anaesthesia Terms and Conditions

Fig 1 Loop of the terminal ileum ready for microscopic observation. Different ‘regions of interest’ are defined. British Journal of Anaesthesia 2002 88, 841-847DOI: (10.1093/bja/88.6.841) Copyright © 2002 British Journal of Anaesthesia Terms and Conditions

Fig 2 Arteriolar diameter. Asterisks indicate significant changes from baseline. *P<0.05; **P<0.01; ***P<0.001. Differences are expressed as changes in percent from baseline values. Each data point is based upon approximately 200 single measurements. Time points: 0=basline; 1=1 h of pLHB; 2=2 h of pLHB; 3=1 h after weaning off pLHB; 4=2 h after weaning off pLHB. British Journal of Anaesthesia 2002 88, 841-847DOI: (10.1093/bja/88.6.841) Copyright © 2002 British Journal of Anaesthesia Terms and Conditions

Fig 3 Blood‐cell velocities in arterioles. (Time points: see Fig. 2.) Asterisks indicate significant changes from baseline. *P<0.05; **P<0.01; ***P<0.001. Differences are expressed as changes in percent from baseline values. Each data point is based upon approximately 200 single measurements. British Journal of Anaesthesia 2002 88, 841-847DOI: (10.1093/bja/88.6.841) Copyright © 2002 British Journal of Anaesthesia Terms and Conditions

Fig 4 Functional capillary density. (Time points: see Fig. 2.) Asterisks indicate significant changes from baseline. *P<0.05; **P<0.01; ***P<0.001. Each column represents the measurements of approximately 30 capillary fields. British Journal of Anaesthesia 2002 88, 841-847DOI: (10.1093/bja/88.6.841) Copyright © 2002 British Journal of Anaesthesia Terms and Conditions

Fig 5 Haemoconcentration and blood cell aggregates within collecting venules following 2 h pLHB and 1 h after weaning off bypass. *The corpuscular blood cells appear as clots within the FITC‐dextran stained (bright) plasma. British Journal of Anaesthesia 2002 88, 841-847DOI: (10.1093/bja/88.6.841) Copyright © 2002 British Journal of Anaesthesia Terms and Conditions

Fig 6 Blood‐cell velocities in submucous venules. (Time points: see Fig. 2.) Asterisks indicate significant changes from baseline. **P<0.01; ***P<0.001. Differences are expressed as changes in percent from baseline values. Each data point is based upon approximately 200 single measurements. British Journal of Anaesthesia 2002 88, 841-847DOI: (10.1093/bja/88.6.841) Copyright © 2002 British Journal of Anaesthesia Terms and Conditions