ChromEMT reveals the in situ chromatin ultrastructure, 3D packing, and organization of DNA. ChromEMT reveals the in situ chromatin ultrastructure, 3D packing,

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Presentation transcript:

ChromEMT reveals the in situ chromatin ultrastructure, 3D packing, and organization of DNA. ChromEMT reveals the in situ chromatin ultrastructure, 3D packing, and organization of DNA. EMT sample volume-DNA-nucleosome chains are black. Chromatin is a structurally disordered 5- to 24-nm granular chain that is packed together at different 3D CVC densities in human interphase nuclei and mitotic chromosomes (red, high density; yellow, medium density; blue, low density). Horng D. Ou et al. Science 2017;357:eaag0025 Published by AAAS