Features of Severe Liver Disease With Portal Hypertension in Patients With Cystic Fibrosis  Jaclyn R. Stonebraker, Chee Y. Ooi, Rhonda G. Pace, Harriet Corvol, Michael R. Knowles, Peter R. Durie, Simon C. Ling  Clinical Gastroenterology and Hepatology  Volume 14, Issue 8, Pages 1207-1215.e3 (August 2016) DOI: 10.1016/j.cgh.2016.03.041 Copyright © 2016 Terms and Conditions

Figure 1 Patients enrolled in the Genetic Modifier Study of CF Liver Disease (CFLD Study) from January 1999 up to July 2013, by age and sex. Patients who were confirmed to have severe CFLD and diagnosed after 30 years (n = 4) were 4 or more SDs above the mean of the normal distribution, which more likely reflects an environmental insult, and therefore were not included in the analysis. Clinical Gastroenterology and Hepatology 2016 14, 1207-1215.e3DOI: (10.1016/j.cgh.2016.03.041) Copyright © 2016 Terms and Conditions

Figure 2 Age of liver disease diagnosis in CFLD subjects by sex. Age distribution of diagnosis of liver disease (portal hypertension) in patients with confirmed CFLD and a reported year of CFLD diagnosis (n = 515). Males are shown by white bars and females are shown in overlapping black bars. Clinical Gastroenterology and Hepatology 2016 14, 1207-1215.e3DOI: (10.1016/j.cgh.2016.03.041) Copyright © 2016 Terms and Conditions