Results of Lab Cancer and the Cell Cycle Unit Five Day 4 Results of Lab Cancer and the Cell Cycle

Opener Why do cells divide and make new cells? 3 minutes. Talk with your table. To repair cells, make new cells- not all cells reproduce like nerve cells

Agenda Results from Lab Intro to Cancer and the Cell Cycle: Podcast: Radiolab (HeLa Cells) on website Cell cycle regulation Cell cycle and cancer

Announcements This Saturday Enter by the commons Practice AP test Be at my room 8:00 AM for bfast Test starts at 8:30 Homework: Read and take notes on Ch 12 Videos: “Cell Cycle” and “Mitosis and Meiosis” Essential Question: How does the cell cycle work and regulate itself?

I can explain the Link between genes, the Cell Cycle and Cancer New Target I can explain the Link between genes, the Cell Cycle and Cancer

The Cell cycle: normally

Mitosis v Meiosis

But before that can happen…

The cell Cycle

Cyclin and Kinase Different proteins, called cyclins, accumulate during a cell’s life span. Tell the cell when to advance to the next stage in the cell cycle Players Cyclin, Cyclin Dependent Kinase (CDK), and Maturation promoting factor (MPF)

The Cell cycle: Not so normally

Number of research papers published using different “cell lines”

So how does our body regulate so we stay healthy?

Reading Read the article: “Cell Division and Cancer” Reading Purpose: What is the connection between the cell cycle, genes and cancer? Mark the text: Number the paragraphs Highlight information related to reading purpose Ask questions Define vocabulary Make connections You have 20 minutes

Making connections EIGHT MINUTES What is the connection between genes, the cell cycle and cancer? On a whiteboard, draw this: On the sides of the triangle: Make connections between ideas at points Be as detailed as possible Genes Cancer The Cell Cycle Tumor supressor, oncogene, checkpoints, mutations

Genes Cancer The Cell Cycle

Exit ticket In your own words, summarize the connection between genes, the cell cycle and cancer Here are some words that should appear in your summary: Cell, cell cycle, checkpoint, signaling pathway, gene, protein, mutation, cancer, gene, tumor-suppressor, oncogene