A 20-Year-Old Man With Fever, Chest Pain, and Lung Nodules

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Presentation transcript:

A 20-Year-Old Man With Fever, Chest Pain, and Lung Nodules Jose Angelo A. De Dios, MD, Adnan A. Javaid, MD, Thalia Mesologites, MD, Bimalin Lahiri, MD, FCCP  CHEST  Volume 140, Issue 5, Pages 1378-1381 (November 2011) DOI: 10.1378/chest.11-0907 Copyright © 2011 The American College of Chest Physicians Terms and Conditions

Figure 1 A, Chest CT scan showing bibasilar nodules. B, Another view of the chest CT scan, showing ill-defined nodules at the bases. CHEST 2011 140, 1378-1381DOI: (10.1378/chest.11-0907) Copyright © 2011 The American College of Chest Physicians Terms and Conditions

Figure 2 Low-power magnification showing an area of loosely organized necrotizing granulomatous inflammation adjacent to normal lung (hematoxylin and eosin, original magnification ×10). CHEST 2011 140, 1378-1381DOI: (10.1378/chest.11-0907) Copyright © 2011 The American College of Chest Physicians Terms and Conditions

Figure 3 Palisading histiocytes surround an area of suppurative necrosis (seen on the right side of the image). Inflammatory cells (left side) surround the histiocytes (hematoxylin and eosin, original magnification ×20). CHEST 2011 140, 1378-1381DOI: (10.1378/chest.11-0907) Copyright © 2011 The American College of Chest Physicians Terms and Conditions

Figure 4 Giant cells are seen in the area of inflammatory reaction surrounding the necrosis (hematoxylin and eosin, original magnification ×20). CHEST 2011 140, 1378-1381DOI: (10.1378/chest.11-0907) Copyright © 2011 The American College of Chest Physicians Terms and Conditions