Progesterone receptor nuclear morphology patterns in breast cancer.

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Progesterone receptor nuclear morphology patterns in breast cancer. Progesterone receptor nuclear morphology patterns in breast cancer. (A) Diffuse pattern: homogeneous and diffuse fine granular distribution in the nuclei of tumour cells (×100). (B) Diffuse pattern: homogeneous and diffuse fine granular distribution in the nuclei of tumour cells (×40). (C) Aggregated pattern: heterogeneous distribution of moderate and large spots in the nuclei of tumour cells (×100). (D) Aggregated pattern: heterogeneous distribution of moderate and large spots in the nuclei of tumour cells (×40). Jacques Bonneterre et al. ESMO Open 2016;1:e000072 Copyright © European Society for Medical Oncology. All rights reserved.