When is it Best to Repeat a 2-Fluoro-2-Deoxy-d-Glucose Positron Emission Tomography/Computed Tomography Scan on Patients with Non-Small Cell Lung Cancer.

Slides:



Advertisements
Similar presentations
Correlation of 18F-FDG Avid Volumes on Pre–Radiation Therapy and Post–Radiation Therapy FDG PET Scans in Recurrent Lung Cancer  Nadya Shusharina, PhD,
Advertisements

Jeffrey M. Griffin, MD, MS, Carolyn E. Reed, MD, Chadrick E
Photodynamic Laser Therapy for Lesions in the Airway
Endoscopic Ultrasound-Guided Fine Needle Aspiration of Mediastinal Lymph Node in Patients With Suspected Lung Cancer After Positron Emission Tomography.
Elizabeth A. David, MD, David T
Jeffrey L. Port, MD, Robert J. Korst, MD, Paul C. Lee, MD, Amanda L
Definitive or Preoperative Chemoradiation Therapy for Esophageal Cancer: Patterns of Care and Survival Outcomes  Meng S. Shao, MD, Andrew T. Wong, MD,
Complete Thoracic Mediastinal Lymphadenectomy Leads to a Higher Rate of Pathologically Proven N2 Disease in Patients With Non-Small Cell Lung Cancer 
Endobronchial Ultrasonography for Positron Emission Tomography and Computed Tomography–Negative Lymph Node Staging in Non-Small Cell Lung Cancer  Masato.
Impact of Race on Outcomes of Patients with Non-small Cell Lung Cancer
Joshua E. Rosen, BASc, Hari B
Standard Uptake Value Predicts Survival in Non–Small Cell Lung Cancer
Ravi Rajaram, MD, MSc, Jennifer L
Phillips B. Harrington, MD, William W. McAlexander, MD, Ayesha S
Lisa M. Brown, MD, MAS, David T. Cooke, MD, Elizabeth A. David, MD 
A Nondivided Intercostal Muscle Flap Further Reduces Pain of Thoracotomy: A Prospective Randomized Trial  Robert James Cerfolio, MD, Ayesha S. Bryant,
Salvage Lung Resection After Definitive Radiation (>59 Gy) for Non-Small Cell Lung Cancer: Surgical and Oncologic Outcomes  Julie E. Bauman, MD, Michael.
Morbidity, Survival, and Site of Recurrence After Mediastinal Lymph-Node Dissection Versus Systematic Sampling After Complete Resection for Non-Small.
Benjamin E. Lee, MD, Mark Shapiro, MD, John R. Rutledge, MAS, Robert J
Cooperative Group Clinical Trials in General Thoracic Surgery: Report From the 2012 Robert Ginsberg Clinical Trials Meeting of the General Thoracic Surgical.
Unexpected Small Bowel Intussusception Caused by Lung Cancer Metastasis on 18F- Fluorodeoxyglucose PET-CT  Jeong Won Lee, MD, Seok-Ki Kim, MD, Ji Won Park,
Direct Cryosurgery for Inoperable Metastatic Disease of the Lung
The True False Negative Rates of Esophageal and Endobronchial Ultrasound in the Staging of Mediastinal Lymph Nodes in Patients With Non-Small Cell Lung.
Video-Assisted Thoracic Surgery Lobectomy: Experience With 1,100 Cases
Meta-Analysis of Positron Emission Tomographic and Computed Tomographic Imaging in Detecting Mediastinal Lymph Node Metastases in Nonsmall Cell Lung Cancer 
Lymph Node Evaluation Achieved by Open Lobectomy Compared With Thoracoscopic Lobectomy for N0 Lung Cancer  Robert E. Merritt, MD, Chuong D. Hoang, MD,
Neither Maximum Tumor Size nor Solid Component Size Is Prognostic in Part-Solid Lung Cancer: Impact of Tumor Size Should Be Applied Exclusively to Solid.
The Incidence and Management of Postoperative Chylothorax After Pulmonary Resection and Thoracic Mediastinal Lymph Node Dissection  Ayesha S. Bryant,
Adding Radiotherapy to Adjuvant Chemotherapy Does Not Improve Survival of Patients With N2 Lung Cancer  Justin A. Drake, MD, David C. Portnoy, MD, Kurt.
Mohamed K. Kamel, MD, Mohamed Rahouma, MD, Benjamin Lee, MD, Sebron W
Philip W. Smith, MD, Hongkun Wang, PhD, Leo M. Gazoni, MD, K
Chris Dickhoff, MD, Max Dahele, MD, PhD, Sayed M
The Efficacy of Restaging Endobronchial Ultrasound in Patients With Non-Small Cell Lung Cancer After Preoperative Therapy  Basil S. Nasir, MBBCh, Ayesha.
Positron Emission Tomography-Computed Tomography for Postoperative Surveillance in Non-Small Cell Lung Cancer  Se Hoon Choi, MD, Young Tae Kim, MD, PhD,
Coexistent Pulmonary Inflammatory Pseudotumor and Carcinoma in One Patient: Does Positron Emission Tomography/Computed Tomography Help  Zhi Zheng, MD,
Basil S. Nasir, MBBCh, Ayesha S. Bryant, MSPH, MD, Douglas J
Asad A. Shah, MD, Mathias Worni, MD, MHS, Christopher R
Utility of Routine PET Imaging to Predict Response and Survival After Induction Therapy for Non-Small Cell Lung Cancer  Stephen A. Barnett, MBBS, Robert.
Use of Amiodarone After Major Lung Resection
Management of Subcutaneous Emphysema After Pulmonary Resection
Abel Gómez-Caro, MD, Pedro Arguis, MD  The Annals of Thoracic Surgery 
Alex K. Bryant, BS, Robert C. Mundt, HSDG, Ajay P. Sandhu, MD, James J
Recurrence and Survival After Segmentectomy in Patients With Prior Lung Resection for Early-Stage Non-Small Cell Lung Cancer  Lisa M. Brown, MD, Brian.
Differences in Patterns of Recurrence in Early-Stage Versus Locally Advanced Non- Small Cell Lung Cancer  Feiran Lou, MD, MS, Camelia S. Sima, MD, MS,
Salvage Operation for Late Recurrence After Stereotactic Body Radiotherapy for Lung Cancer: Two Patients With No Viable Cancer Cells  Naohiro Taira, MD,
Surgically Managed Clinical Stage IIIA–Clinical N2 Lung Cancer in The Society of Thoracic Surgeons Database  Daniel Boffa, MD, Felix G. Fernandez, MD,
Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration for Differentiating N0 Versus N1 Lung Cancer  Kazuhiro Yasufuku, MD, PhD, Takahiro Nakajima,
A Systematic Review of Restaging After Induction Therapy for Stage IIIa Lung Cancer: Prediction of Pathologic Stage  Sara de Cabanyes Candela, MD, Frank.
Phillip G. Rowse, MD, Dawn E
Daily Chest Roentgenograms Are Unnecessary in Nonhypoxic Patients Who Have Undergone Pulmonary Resection by Thoracotomy  Robert James Cerfolio, MD, Ayesha.
Accuracy of Fluorodeoxyglucose-Positron Emission Tomography Within the Clinical Practice of the American College of Surgeons Oncology Group Z4031 Trial.
Douglas E. Paull, MD, Glenda M. Updyke, PA-C, Michael A
Arman Kilic, BS, Matthew J. Schuchert, MD, Brian L
Distribution and Likelihood of Lymph Node Metastasis Based on the Lobar Location of Nonsmall-Cell Lung Cancer  Robert J. Cerfolio, MD, Ayesha S. Bryant,
Margin Distance Does Not Influence Recurrence and Survival After Wedge Resection for Lung Cancer  Giulio Maurizi, MD, Antonio D’Andrilli, MD, Anna Maria.
Stephen R. Broderick, MD, MPHS, Aalok P. Patel, BS, BA, Traves D
The Removal of Chest Tubes Despite an Air Leak or a Pneumothorax
Neoadjuvant Chemoradiation Therapy Is Beneficial for Clinical Stage T2 N0 Esophageal Cancer Patients Due to Inaccurate Preoperative Staging  Jennifer.
Robert J. Cerfolio, MD, FACS, FCCP, Ayesha S. Bryant, MSPH, MD 
Role of Positron Emission Tomography/Computed Tomography Findings for Adjuvant Chemotherapy Indications in Stage T1b-2aN0M0 Lung Adenocarcinoma  Shinsuke.
Prognostic Role of Positron Emission Tomography and High-Resolution Computed Tomography in Clinical Stage IA Lung Adenocarcinoma  Hirofumi Uehara, MD,
Christopher Hazzard, BS, Andrea S. Wolf, MD, Mary B
Survival and Outcomes of Pulmonary Resection for Non-Small Cell Lung Cancer in the Elderly: A Nested Case-Control Study  Robert J. Cerfolio, MD, Ayesha.
The clinical stage of non–small cell lung cancer as assessed by means of fluorodeoxyglucose–positron emission tomographic/computed tomographic scanning.
Mark I. Block, MD  The Annals of Thoracic Surgery 
Domenico Galetta, MD, PhD, Lorenzo Spaggiari, MD, PhD 
Early Surgical Results After Pneumonectomy for Non-Small Cell Lung Cancer are not Affected by Preoperative Radiotherapy and Chemotherapy  Tomas Gudbjartsson,
Treating Locally Advanced Disease: An Analysis of Very Large, Hilar Lymph Node Positive Non-Small Cell Lung Cancer Using the National Cancer Data Base 
Induction Chemoradiation Is Not Superior to Induction Chemotherapy Alone in Stage IIIA Lung Cancer  Asad A. Shah, MD, Mark F. Berry, MD, Ching Tzao, MD,
Meghan R. Flanagan, MD, Thomas K. Varghese, MD, MS, Leah M
Presentation transcript:

When is it Best to Repeat a 2-Fluoro-2-Deoxy-d-Glucose Positron Emission Tomography/Computed Tomography Scan on Patients with Non-Small Cell Lung Cancer Who Have Received Neoadjuvant Chemoradiotherapy?  Robert James Cerfolio, MD, Ayesha S. Bryant, MSPH, MD  The Annals of Thoracic Surgery  Volume 84, Issue 4, Pages 1092-1097 (October 2007) DOI: 10.1016/j.athoracsur.2007.05.050 Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Algorithm for the restaging of patients with stage IIIa (N2) non-small cell lung cancer after neoadjuvant chemoradiotherapy using cisplatinum-based chemotherapy and concurrent high dose (60 Gy or greater) of radiotherapy. (CT = computed tomography; maxSUV = maximum standardized uptake value; PET = positron emission tomography.) The Annals of Thoracic Surgery 2007 84, 1092-1097DOI: (10.1016/j.athoracsur.2007.05.050) Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Accuracy of integrated 2-fluoro-2-deoxy-d-glucose positron emission tomography (PET)/computed tomography scan for restaging, overall (gray bars) and for N2 disease (black bars) based on the time interval between the last dose of radiotherapy and the repeat PET scan. The Annals of Thoracic Surgery 2007 84, 1092-1097DOI: (10.1016/j.athoracsur.2007.05.050) Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Receiver operating characteristic curve (black line) with 95% confidence intervals (gray lines) shows the optimal time to perform a repeat positron emission tomography scan after neoadjuvant chemoradiotherapy therapy for overall staging, which was 26 days after last dose of radiotherapy (area under the curve, diagonal line, 0.88). The Annals of Thoracic Surgery 2007 84, 1092-1097DOI: (10.1016/j.athoracsur.2007.05.050) Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Receiver operating characteristic curve (black line) with 95% confidence intervals (gray lines) shows the optimal time to perform a repeat positron emission tomography scan after neoadjuvant chemoradiotherapy for N2 restaging, which was 29 days after the last dose of radiotherapy (area under the curve, diagonal line, 0.82). All 97 patients with IIIa (N2) disease had biopsy-proven N2 nodes and then underwent rebiopsy or removal of the same node after neoadjuvant therapy. The Annals of Thoracic Surgery 2007 84, 1092-1097DOI: (10.1016/j.athoracsur.2007.05.050) Copyright © 2007 The Society of Thoracic Surgeons Terms and Conditions