Electrical Synapses: Rectification Demystified

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Electrical Synapses: Rectification Demystified Eve Marder  Current Biology  Volume 19, Issue 1, Pages R34-R35 (January 2009) DOI: 10.1016/j.cub.2008.11.008 Copyright © 2009 Elsevier Ltd Terms and Conditions

Figure 1 Cartoon schematic of two cells coupled by a rectifying electrical junction. Left: depolarizing current (I) injected into cell A depolarizes cell A (voltage VA) and to a lesser degree, cell B (VB). On the other hand, hyperpolarization of cell A has little effect on the VB. This indicates that depolarizing current passes preferentially from cell A to cell B. This is verified by current injections into cell B, that show that depolarization of cell B has little effect on the voltage in cell A, but hyperpolarization of cell B effectively hyperpolarizes cell A. (Thanks to Marie Goeritz for help with preparing this figure.) Current Biology 2009 19, R34-R35DOI: (10.1016/j.cub.2008.11.008) Copyright © 2009 Elsevier Ltd Terms and Conditions