Fatal Early-Onset Epstein-Barr Virus–Associated Posttransplantation Lymphoproliferative Disease after Successful Adult Dual-Unit Umbilical Cord Blood.

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Presentation transcript:

Fatal Early-Onset Epstein-Barr Virus–Associated Posttransplantation Lymphoproliferative Disease after Successful Adult Dual-Unit Umbilical Cord Blood Transplantation Say-Bee Poh, Liang-Tsai Hsiao, Ching-Fen Yang, Tzeon-Jye Chiou, Po-Min Chen Biology of Blood and Marrow Transplantation Volume 11, Issue 9, Pages 732-733 (September 2005) DOI: 10.1016/j.bbmt.2005.05.011 Copyright © 2005 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 EBV detection in sample series. Detection of EBV is shown in mononuclear cells of peripheral blood, bone marrow, and lymphoma tissue at the diagnosis of PTLD by using EBV-specific polymerase chain reaction. No EBV was detected in the mononuclear cells of cord blood from 2 donors or the peripheral blood or marrow cells from the patient before transplantation. EBV was identified in all samples only after transplantation. The Daudi cell line was used as the positive control. CBA, CBB, and NP indicate cord blood A, cord blood B, and nasopharynx tissue, respectively. Pre-PB/BM and Post-PB/BM indicate samples from peripheral blood and bone marrow before and after UCBT, respectively. Biology of Blood and Marrow Transplantation 2005 11, 732-733DOI: (10.1016/j.bbmt.2005.05.011) Copyright © 2005 American Society for Blood and Marrow Transplantation Terms and Conditions