Markers of lung injury in C57Bl/6 mice post IT-LPS.

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Presentation transcript:

Markers of lung injury in C57Bl/6 mice post IT-LPS. Markers of lung injury in C57Bl/6 mice post IT-LPS. C57Bl/6 mice were instilled via IT route with 50 µg LPS. Markers of endothelial barrier permeability (A) and alveolar epithelial cell damage by assessing RAGE expression (B) were assessed daily. The total number of granulocytes in BAL fluid was also enumerated per mL (C). The percentage (D) and number (E) of neutrophils were analysed using flow cytometry. ANOVA, analysis of variance; BAL, bronchoalveolar lavage; IT-LPS, intratracheal lipopolysaccharide; RAGE, receptor for advanced glycation end. Siân Lax et al. BMJ Open Resp Res 2014;1:e000014 ©2014 by British Thoracic Society