Complete remission of a primary rectal lymphoma on ulcerative colitis, after withdrawal of azathioprine and infliximab Antonio López San Román, Manuel.

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Presentation transcript:

Complete remission of a primary rectal lymphoma on ulcerative colitis, after withdrawal of azathioprine and infliximab Antonio López San Román, Manuel Van Domselaar, Miguel Rivero, Clara Redondo, Rosario Arribas, Antonio Rey Journal of Crohn's and Colitis Volume 2, Issue 1, Pages 93-96 (March 2008) DOI: 10.1016/j.crohns.2007.10.005 Copyright © 2007 European Crohn's and Colitis Organisation Terms and Conditions

Figure 1 Biopsy showing monomorphic large B-cell lymphoma. Journal of Crohn's and Colitis 2008 2, 93-96DOI: (10.1016/j.crohns.2007.10.005) Copyright © 2007 European Crohn's and Colitis Organisation Terms and Conditions

Figure 2 Tumor cells diffusely positive for CD20. Journal of Crohn's and Colitis 2008 2, 93-96DOI: (10.1016/j.crohns.2007.10.005) Copyright © 2007 European Crohn's and Colitis Organisation Terms and Conditions

Figure 3 Positive immunostaining for LMP-1. Journal of Crohn's and Colitis 2008 2, 93-96DOI: (10.1016/j.crohns.2007.10.005) Copyright © 2007 European Crohn's and Colitis Organisation Terms and Conditions

Figure 4 In situ hybridization for EBER. Journal of Crohn's and Colitis 2008 2, 93-96DOI: (10.1016/j.crohns.2007.10.005) Copyright © 2007 European Crohn's and Colitis Organisation Terms and Conditions

Figure 5 Polymorphic plasma cell hyperplasia in the resected surgical specimen after withdrawal of immunosuppression. The histological study showed only plasma cell proliferation, with frequent large cells but no lymphoma. Journal of Crohn's and Colitis 2008 2, 93-96DOI: (10.1016/j.crohns.2007.10.005) Copyright © 2007 European Crohn's and Colitis Organisation Terms and Conditions