Pathologic Findings and Long-Term Results After Surgical Treatment for Pulmonary Sarcomatoid Tumors: A Multicenter Analysis Filippo Lococo, MD, Cristian.

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Pathologic Findings and Long-Term Results After Surgical Treatment for Pulmonary Sarcomatoid Tumors: A Multicenter Analysis Filippo Lococo, MD, Cristian Rapicetta, PhD, Giuseppe Cardillo, PhD, Alessandro Stefani, MD, Stefano Margaritora, MD, Giovanni Leuzzi, MD, Giulio Rossi, MD, Leonardo Petracca Ciavarella, MD, Uliano Morandi, MD, Francesco Facciolo, MD, Tommaso Ricchetti, MD, Alfredo Cesario, MD, Massimiliano Paci, MD The Annals of Thoracic Surgery Volume 103, Issue 4, Pages 1142-1150 (April 2017) DOI: 10.1016/j.athoracsur.2016.08.114 Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Examples of sarcomatoid carcinoma. (A) Pleomorphic carcinoma (hematoxylin-eosin; ×150 magnification) composed of conventional (NSCLC) (eg, squamous cell carcinoma, on left) and spindle cell carcinoma (on right). (B) Pure spindle cell carcinoma (hematoxylin-eosin; ×200 magnification). (C) Pure giant cell carcinoma (hematoxylin-eosin; ×200 magnification). (D) Mixed spindle cell and giant cell carcinoma (hematoxylin-eosin; ×200 magnification). The Annals of Thoracic Surgery 2017 103, 1142-1150DOI: (10.1016/j.athoracsur.2016.08.114) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 (A and B) Vascular invasion by sarcomatoid carcinoma occluding the vessels (hematoxylin-eosin; ×200 magnification). (C and D) Pan cytokeratin (clone AE1/AE3) stain (immunohistochemistry; ×200 magnification). The Annals of Thoracic Surgery 2017 103, 1142-1150DOI: (10.1016/j.athoracsur.2016.08.114) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Overall long-term survival (LTS) in entire cohort of patients. The Annals of Thoracic Surgery 2017 103, 1142-1150DOI: (10.1016/j.athoracsur.2016.08.114) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Long-term survival (LTS) function according to (A) clinical stage (c-stage), (B) surgical radicality), (C) pathologic stage (p-stage), (D) presence of vascular emboli, and (E) occurrence of tumor relapse. The Annals of Thoracic Surgery 2017 103, 1142-1150DOI: (10.1016/j.athoracsur.2016.08.114) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions