C. William Cole, MD, FRCS a, Janis Bormanis, MD, FRCPC b, Gregory K

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Presentation transcript:

Ancrod versus heparin for anticoagulation during vascular surgical procedures C.William Cole, MD, FRCS a, Janis Bormanis, MD, FRCPC b, Gregory K. Luna a, MD, George Hajjar, MD, FRCSC a, Graeme G. Barber, MD, FRCSC a, Kenneth A. Harris, MD, FRCSC a, William F. Brien, MD, FRCPC b Journal of Vascular Surgery Volume 17, Issue 2, Pages 288-293 (February 1993) DOI: 10.1016/0741-5214(93)90414-H Copyright © 1993 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 1 Schematic representation of thrombin (left) and ancrod (right) and their proteolytic actions on fibrinogen and factor XIII (FSF). Ancrod cleaves A-fibrinopeptides but not fibrinopeptide-B from fibrinogen. In the chromatographic assay of fibrinopeptide fragments, letters (e.g., AY) used to described peptides of different molecular weight or polymerized (AP) fragments. Journal of Vascular Surgery 1993 17, 288-293DOI: (10.1016/0741-5214(93)90414-H) Copyright © 1993 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions