Single Cell Mass Cytometry Identifies T-Regulatory Cell Subsets Associated with ECP Response in Chronic GVHD Madan H. Jagasia, MD, MBBS, MS, Tanya Basu,

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Single Cell Mass Cytometry Identifies T-Regulatory Cell Subsets Associated with ECP Response in Chronic GVHD Madan H. Jagasia, MD, MBBS, MS, Tanya Basu, MA, PhD, MRCP, Brian G. Engelhardt, MD, Heidi Chen, PhD, William Clark, MD, MS, Edmund K. Waller, MD, PhD, Cynthia Giver, PhD, Yi-Bin Chen, MD, Bipin N. Savani, MD, Adetola A. Kassim, MD, MS, Dae Kwang Jung, BS, Hannah Polikowsky, Reda Benmebarek, Susanne Heck, Richard Ellis, Thomas Seidl, G. Mufti, Jonathan Irish, PhD, Shahram Kordasti, MSc, MD, PhD Biology of Blood and Marrow Transplantation Volume 22, Issue 3, Pages S400-S401 (March 2016) DOI: 10.1016/j.bbmt.2015.11.928 Copyright © 2016 Terms and Conditions

Fig 1 (A) viSNE plot of a patient showing decrease in TNFα and IFNγ expression with ECP. The viSNE plots are from CD3+ gated T cells and coloring channels are TNFα (left) and IFNγ (right). (B) Figure 1B. TNF+ expression among FOXP3 high Treg: Time trend difference among responders (CR+PR) and non-responders (SD+PD). Biology of Blood and Marrow Transplantation 2016 22, S400-S401DOI: (10.1016/j.bbmt.2015.11.928) Copyright © 2016 Terms and Conditions