Mammalian Target of Rapamycin Inhibitor–Associated Stomatitis in Hematopoietic Stem Cell Transplantation Patients Receiving Sirolimus Prophylaxis for.

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Mammalian Target of Rapamycin Inhibitor–Associated Stomatitis in Hematopoietic Stem Cell Transplantation Patients Receiving Sirolimus Prophylaxis for Graft-versus-Host Disease Alessandro Villa, Ali Aboalela, Katharine A. Luskin, Corey S. Cutler, Stephen T. Sonis, Sook Bin Woo, Douglas E. Peterson, Nathaniel S. Treister Biology of Blood and Marrow Transplantation Volume 21, Issue 3, Pages 503-508 (March 2015) DOI: 10.1016/j.bbmt.2014.11.680 Copyright © 2015 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 Fifty-four year-old female with a history of acute myeloid leukemia after HSCT on sirolimus and tacrolimus who developed 2 painful aphthous-like tongue ulcers. Biology of Blood and Marrow Transplantation 2015 21, 503-508DOI: (10.1016/j.bbmt.2014.11.680) Copyright © 2015 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 2 Histological features of oral mucosa exhibiting deep ulcer involving muscle at the base (A) and granulation tissue with acute and chronic inflammation and myositis (B). Biology of Blood and Marrow Transplantation 2015 21, 503-508DOI: (10.1016/j.bbmt.2014.11.680) Copyright © 2015 American Society for Blood and Marrow Transplantation Terms and Conditions