Volume 2, Issue 4, Pages (July 2016)

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Volume 2, Issue 4, Pages 337-339 (July 2016) Minocycline pigmentation of the vulva masquerading as a melanocytic lesion  Mathew Loesch, DO, PhD, Laura Jordan, DO, Kord S. Honda, MD, Roya Rezaee, MD, Kevin Cooper, MD  JAAD Case Reports  Volume 2, Issue 4, Pages 337-339 (July 2016) DOI: 10.1016/j.jdcr.2016.07.003 Copyright © 2016 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 Minocycline pigmentation of the vulva. Irregular pigmentation patch seen on the patient's vulva during examination. JAAD Case Reports 2016 2, 337-339DOI: (10.1016/j.jdcr.2016.07.003) Copyright © 2016 American Academy of Dermatology, Inc. Terms and Conditions

Fig 2 Histopathologic findings from the pigmented lesion biopsy taken from the vestibule/periurethral area. Spongiosis of the epithelium and moderate to numerous superficial melanophages were seen on histology. (Hematoxylin-eosin stain; original magnification: ×20.) JAAD Case Reports 2016 2, 337-339DOI: (10.1016/j.jdcr.2016.07.003) Copyright © 2016 American Academy of Dermatology, Inc. Terms and Conditions

Fig 3 Left forearm examination shows a small portion of the widespread, irregular speckled macules and patches of grey dyspigmentation present diffusely throughout the patient's skin surface. JAAD Case Reports 2016 2, 337-339DOI: (10.1016/j.jdcr.2016.07.003) Copyright © 2016 American Academy of Dermatology, Inc. Terms and Conditions

Fig 4 Histopathologic findings from the prior biopsy after staining with iron. The biopsy section shows positive areas of black and brown pigment in the papillary dermis consistent with minocycline dermal pigmentation. (Iron staining; original magnification: ×40.) JAAD Case Reports 2016 2, 337-339DOI: (10.1016/j.jdcr.2016.07.003) Copyright © 2016 American Academy of Dermatology, Inc. Terms and Conditions